Results 81 to 90 of about 22,345 (254)

Percutaneous Deployment of the Sinus‐SuperFlex‐DS Stent for Hybrid Stage I Palliation in Neonates Weighing ≤ 2.5 kg: A Multicenter Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel, Jochen Grohmann, Katarzyna Gendera, Götz Müller, Harald Bertram, Matthias Sigler, Dietmar Schranz, Christian Jux, Markus Khalil   +8 more
wiley   +1 more source

HLH-29 Regulatory Network.

, 2013
A) Functional annotation and distribution of HLH-29 targets as predicted by DAVID analysis. Brackets indicate the number of target genes in each cluster.
Gaolin Zheng Milledge (393588), Casonya M. Johnson (393589), Thanh K. Quach (393586), Kun Wang (134525), Han Ting Chou (393587)   +4 more
core   +1 more source

Ruxolitinib Pharmacokinetics and Exposure–Toxicity Relationship in Hematologic Malignancies and Immune‐Mediated Diseases: A Prospective Observational Study

Clinical Pharmacology &Therapeutics, EarlyView.
Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet, Sara C. Meyer, Francesco Grandoni, Emmanuel Haefliger, Monika Nagy‐Hulliger, Jörg P. Halter, Jakob R. Passweg, David Haefliger, Carine Bardinet, Laurent A. Decosterd, Monia Guidi, François R. Girardin   +11 more
wiley   +1 more source

Evaluating hemophagocytic lymphohistiocytosis criteria in patients with drug-induced hypersensitivity syndrome

JAAD Reviews
Background: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of uncontrolled immune activation causing fever, cytopenias, hepatosplenomegaly, and organ dysfunction. Diagnosis is made using the HLH-2004 or -2009 criteria.
Hannah Bulosan, BS, Maryam Yousefiasl, MPH, H-MBA, Leah D. Kovacs, BFA, Michi M. Shinohara, MD, Anna L. Cogen, MD, PhD   +4 more
doaj   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Dopamine Transporter Imaging‐Based Radiomics for Predicting 4‐Year Motor Progression (Unified Parkinson's Disease Rating Scale Part III) in Parkinson's Disease

iRADIOLOGY, EarlyView.
Magnetic resonance imaging (MRI)‐guided dopamine transporter (DAT) radiomics combined with machine learning showed promising performance for predicting 4‐year motor progression in Parkinson's disease. Ensemble voting fusion markedly improved discrimination compared with individual base models, with stable predictive features mainly derived from ...
Xiaoxuan Fan, Yanghan Chen, Junfeng Lin, Zenwen Han, Jianqiang Ye, Lili Lin, Hong Zhang, Ang Li, Han Jiang   +8 more
wiley   +1 more source

Schematized hlh-4 functions.

, 2018
(A) Overall logic of hlh-4/terminal selector function. “0” indicates gene/feature not expressed; “1” indicates expressed (this binary scheme is a simplification).
Saeed Tavazoie (7618), Oliver Hobert (70540), Neda Masoudi (541180), Leesun Ryu (651729), Lori Glenwinkel (4729329), Kyuhyung Kim (651731)   +5 more
core   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

Evaluation of children with haemophagocytic lymphohistiocytosis (HLH) at Red Cross War Memorial Children's Hospital 1991-2010

, 2011
Includes bibliographical references.Haemophagocytic Lymphohistiocytosis (HLH) is a rare haematological disorder in children. However, this is probably an underestimation due to the difficulty in diagnosing the disease.
Switala, Juli
core  

Successfully performed video capsule endoscopy in an 8‐month‐old infant weighing 7.5 kg

JPGN Reports, EarlyView.
Abstract Video capsule endoscopy (VCE) is a well‐established diagnostic tool for examining the small bowel. Limited data exist on its use in infants. To our knowledge, we present the first detailed case of a successful PillCam®SB3‐VCE performed in an 8‐month‐old infant weighing 7.5 kg with suspected small bowel bleeding following allogeneic ...
Paul‐Christoph Zeisler, Robert Thimme, Ulrike Teufel‐Schaefer, Michael Schultheiß   +3 more
wiley   +1 more source