Results 71 to 80 of about 24,724 (214)

Natural-killer cell cytotoxicity as a diagnostic and prognostic marker for adult patients with secondary hemophagocytic lymphohistiocytosis: a prospective phase II observational study

Therapeutic Advances in Hematology, 2021
Background: Hemophagocytic lymphohistiocytosis (HLH) can be life-threatening if not detected and treated appropriately. The diagnosis of HLH can be confusing due to other similar febrile diseases that present with cytopenia.
Eun-Jee Oh, Jae-Ho Yoon, Ki Hyun Park, Hyun Joo Bae, So Jeong Yun, Gi June Min, Sung-Soo Park, Silvia Park, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Seok-Goo Cho, Kyungja Han, Jong Wook Lee   +17 more
doaj   +1 more source

Clinical and genetic findings for 18 HLH patients with identified mutations in HLH-related genes.

, 2014
Normal NK cell activity range: 31.54–41.58%.Normal sCD25 value:
Ran Tang (175386), Junyuan Qi (631286), Jijun Wang (167807), Yini Wang (410389), Jia Zhang (187802), Lihong Li (478410), Liping Ye (631287), Ling Ye (111749), Zhao Wang (145195), Qing Wei (191790)   +9 more
core   +1 more source

Improved hemophagocytic lymphohistiocytosis index predicts prognosis of adult Epstein-Barr virus-associated HLH patients

, 2022
Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (EBV-HLH) is a common subtype of HLH with heterogeneous clinical presentations from self-limited to death, of which adults are worse than children.
Zhengjie Hua (14278460), Heshan Zou (14278463), Menghan Liu (3413381), Yini Wang (410389), Ruoxi Zhang (2863475), Zhao Wang (145195), Shuyan Yao (14278454), Lingbo He (14278457)   +7 more
core   +1 more source

Beyond the Individual: Multisite Population‐Level Consequences of Road Mortality on a Declining Mammal

Animal Conservation, EarlyView.
We used a comparative study design to quantify population densities, structure, survival, cause‐specific mortality and female productivity in four West‐European hedgehog (Erinaceus europaeus) populations, and to forecast the impact of road mortality on population viability.
Lauren J. Moore, Silviu O. Petrovan, Adam J. Bates, Helen L. Hicks, Philip J. Baker, Sarah E. Perkins, David E. Wembridge, Richard W. Yarnell   +7 more
wiley   +1 more source

Evaluating hemophagocytic lymphohistiocytosis criteria in patients with drug-induced hypersensitivity syndrome

JAAD Reviews
Background: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of uncontrolled immune activation causing fever, cytopenias, hepatosplenomegaly, and organ dysfunction. Diagnosis is made using the HLH-2004 or -2009 criteria.
Hannah Bulosan, BS, Maryam Yousefiasl, MPH, H-MBA, Leah D. Kovacs, BFA, Michi M. Shinohara, MD, Anna L. Cogen, MD, PhD   +4 more
doaj   +1 more source

Recurrent parvovirus B19 viremia resulting in two episodes of hemophagocytic lymphohistiocytosis

Virology Journal, 2022
Background Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory condition with uncontrolled activation of lymphocytes and macrophages. Besides a primary (genetic) form, HLH can also be triggered by malignant, autoimmune and infectious diseases.
Hans Martin Orth, Andre Fuchs, Nadine Lübke, Björn-Erik Ole Jensen, Tom Luedde   +4 more
doaj   +1 more source

CNS Involvement in HLH (CNS-HLH)

, 2017
CNS disease is considered to be a result of the pathologic immune response in HLH. CNS involvement is frequently found at diagnosis or can occur anytime in the further course of systemic HLH but has also been reported as primary or only manifestation ...
Beutel, K, AnnaCarin Horne, Karin Beutel, Horne, A,   +3 more
core   +1 more source

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM)

Journal of Magnetic Resonance Imaging, EarlyView.
Francesca Raimondi, Inga Voges, Lamia Ait‐Ali, Sonya Babu‐Narayan, Rene Botnar, Barbara Burkhardt, Adrienne Campbell‐Washburn, Dominik Daniel Gabbert, Georg Hansmann, Willem A. Helbing, Hasan Hosan, Sylvia Krupickova, Heiner Latus, Duarte Martins, Colin McMahon, Christian Meierhofer, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Claudia Prieto, Milan Prsa, Kuberan Pushparajah, José F. Rodríguez Palomares, Samir Sarikouch, Lars Grosse‐Wortman, F. Gerald Greil, Heynric Grotenhuis   +26 more
wiley   +1 more source

Multiscale Modeling of a Geometrically Tunable Shunt for Growing Pediatric Patients With Single Ventricle Physiology

Artificial Organs, EarlyView.
Here we investigated the development of a geometrically tunable blood for patients with single ventricle physiology. Two multiscale cardiovascular models were customized and implemented at timepoints spanning across the beginning and end of the shunt‐use period.
Ellen E. Garven, Ethan Kung, Randy M. Stevens, Christopher B. Rodell, Amy L. Throckmorton   +4 more
wiley   +1 more source

Classification, clinical manifestation and diagnosis of HLH

, 2018
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening immune dysregulation disease. It can be subdivided into a primary, genetic form and a secondary form that complicates diverse infections, autoimmune or autoinflammatory disorders, and ...
Volkmer, Benjamin, Ehl, Stephan, Pachlopnik Schmid, Jana; https://orcid.org/, Janka, Gritta, Abla, Oussama   +4 more
core   +1 more source