Results 91 to 100 of about 22,345 (254)
Hemophagocytic lymphohistiocytosis (HLH) is an immune-regulatory disorder characterized by excessive production of inflammatory cytokines. The treatment recommendations of the HLH-1994 and HLH-2004 protocols have long been used in HLH therapy, but some ...
Qing Zhang +12 more
doaj +1 more source
Treatment of MAS and HLH [PDF]
Macrophage activation syndrome (MAS) is a life-threatening complication of inflammatory disease, occurring secondary to a complex interplay of genetic factors, drugs, infectious agents and immunological anomalies. Early identification and aggressive treatment are mandatory to prevent fatal evolution.
openaire +1 more source
Clinical and genetic findings for 18 HLH patients with identified mutations in HLH-related genes.
Normal NK cell activity range: 31.54–41.58%.Normal sCD25 value:
Ran Tang (175386) +9 more
core +1 more source
Effect of MET on cAMP response of MLTC-1 cells to hLH or FSK/sub-hLH.
(A), (C) Real-time recording of luminescence under stimulation of MLTC-1 cells by hLH or FSK/sub-hLH in the presence of 0 to 1000μM MET. (B), (D) Dose-dependent effects of MET determined on hLH and FSK/sub-hLH responses respectively, by the Area Under ...
Danièle Klett (252303) +3 more
core +1 more source
5D Flow MRI Reveals Respiration‐Driven Changes in Blood Flow Energetics in Congenital Heart Disease
ABSTRACT Purpose Hemodynamic monitoring is essential for patients with right‐sided congenital heart disease (CHD). Respiration may have an increased impact on pulmonary flow in these patients that cannot be assessed by standard tools including 4D flow MRI. This study uses 5D flow MRI to assess respiratory‐cycle variations in flow energetics in patients
Thara Nallamothu +7 more
wiley +1 more source
: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome. Complement component 3 (C3), a central effector molecule in 3 separate complement pathways, has been linked to inflammatory diseases.
Xuemei Shu +6 more
doaj +1 more source
Diagnosis and treatment of HLH in adults.
Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening syndrome of uncontrolled immune activation. It was initially recognized in children, where it occurs primarily as an inherited syndrome related to homozygous null mutations in immune response genes involved in cytotoxic T cell and NK cell function.
PORTER, Rebecca, BERLINER, Nancy
openaire +2 more sources
Riding out the storm: Behavioural responses of a large herbivore to high‐Arctic winds
Using 11 years of GPS data from 61 muskoxen in Northeast Greenland, we show how increasing wind speed and Arctic storms reshape movement modes and habitat selection. Muskoxen respond by bedding in dense vegetation, prioritizing energy conservation over foraging, revealing a simple behavioural strategy with potential fitness consequences under ...
Floris M. van Beest +2 more
wiley +1 more source
Average temperature as a marker of lymphoma-associated HLH [PDF]
Methods: This retrospective analysis aimed to assess whether a 12-hour mean temperature (measured around either diagnosis of HLH or peak ferritin value) has value as a quick and simple diagnostic test for HLH in people with lymphoproliferative disease ...
Goddard, J. +3 more
core +1 more source

