Results 91 to 100 of about 24,724 (214)

C3 as a predictive and prognostic biomarker in adult hemophagocytic lymphohistiocytosis: a large cohort study in China

Blood Advances
: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome. Complement component 3 (C3), a central effector molecule in 3 separate complement pathways, has been linked to inflammatory diseases.
Xuemei Shu, Xinjie Gao, Yujun Dai, Yuxiang Wang, Yilin Liu, Dawei Wang, Tao Guo   +6 more
doaj   +1 more source

HLH-29 Regulates ftn-1 Expression.

, 2013
(A) Schematic representation of the ftn-1 transgenes used in this study. Empty triangle, predicted HLH-30 binding site (CACGTG); filled triangle, predicted HLH-29 binding sites (CATGCG or CACGCG) with arrows indicating the corresponding orientations ...
Gaolin Zheng Milledge (393588), Casonya M. Johnson (393589), Thanh K. Quach (393586), Kun Wang (134525), Han Ting Chou (393587)   +4 more
core   +1 more source

Effect of PRC1 mutants on HLH-3 protein levels.

, 2022
Quantification of the fluorescence levels (arbitrary units) in AIY neurons of HLH-3 protein (hlh-3endo::mNeonGreen (vlc28)) at epidermal enclosure embryonic stage. Each dot represents one neuron.
Carole Couillault (271357), Vincent Bertrand (12601874), Guillaume Bordet (12601865), Konstantina Filippopoulou (12601871), Fabien Soulavie (12601868)   +4 more
core   +1 more source

Metagenomic detection and characterization of RNA viruses associated with Rhipicephalus linnaei (Audouin, 1826) ticks from the Amazon, Pará, Brazil

Medical and Veterinary Entomology, EarlyView.
Metagenomic analysis of Rhipicephalus linnaei from the Brazilian Amazon revealed the presence of RNA viruses belonging to the families Chuviridae, Phenuiviridae, Orthomyxoviridae and Rhabdoviridae. This study reports the first detection of Brown dog tick mivirus 1 and Brown dog tick phlebovirus 2 in Brazil, based on genomic characterization and ...
Lucas Henrique da Silva e Silva, Sandro Patroca da Silva, Fábio Silva da Silva, Leonardo Henrique Almeida Hernández, Daniel Damous Dias, Sâmia Luzia Sena da Silva, Lúcia Aline Moura Reis, Hanna Carolina Farias Reis, Bruna Laís Sena do Nascimento, Roberto Carlos Feitosa Brandão, Durval Bertram Rodrigues Vieira, Bruno Tardelli Diniz Nunes, Ana Cecília Ribeiro Cruz, Joaquim Pinto Nunes Neto   +13 more
wiley   +1 more source

Pediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Hospitalizations in the United States

Pediatric Dermatology, EarlyView.
ABSTRACT Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare life‐threatening mucocutaneous reactions that remain poorly characterized in pediatric populations. Using the Healthcare Cost and Utilization Project (HCUP) Kids' Inpatient Database (KID), the prevalence of SJS/TEN hospitalizations declined from 0.02% in 2016 to 0.009%
Shazli Razi, Priya Agarwal, Gaurav N. Pathak, Christian Kaunzinger, Aaron Morgan, Babar K. Rao   +5 more
wiley   +1 more source

Average temperature as a marker of lymphoma-associated HLH [PDF]

Methods: This retrospective analysis aimed to assess whether a 12-hour mean temperature (measured around either diagnosis of HLH or peak ferritin value) has value as a quick and simple diagnostic test for HLH in people with lymphoproliferative disease ...
Goddard, J., Clark, C., Morley, N., Tattersall, R.   +3 more
core   +1 more source

Clinicogenetic Characterization of H Syndrome in a South African Child

Pediatric Dermatology, EarlyView.
ABSTRACT H syndrome is a rare autosomal recessive genodermatosis caused by loss‐of‐function SLC29A3 variants, combining hyperpigmented indurated plaques and hypertrichosis with life‐threatening autoinflammation. We report a 5‐year‐old South African girl of first‐cousin parents who presented with hyperinflammation mimicking macrophage activation ...
Tshimogo Tswelopele Sathekge, Claude Bailly   +1 more
wiley   +1 more source

Inherited Hemophagocytic Lymphohistiocytosis (HLH)

, 2010
Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal immune disorder characterized by uncontrolled lymphocyte- and macrophage-activation.
Pachlopnik Schmid, Jana; https://orcid.org/, de Saint Basile, G, de Saint Basile G, Pachlopnik Schmid J, G. de Saint Basile, J. Pachlopnik Schmid   +5 more
core   +1 more source

Restoring, Protecting, and Expanding Abortion Access in the United States: Seeking Consensus Through the Delphi Method

Perspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Introduction The Dobbs v. Jackson Women's Health Organization United States (US) Supreme Court decision exacerbated inequitable access to abortion rights in the United States. This study aimed to determine the degree of agreement on which strategies should be prioritized to restore, protect, and expand abortion access. Methodology From July to
Sarah Pickering, Meredith Manze, Jeffrey V Lazarus, Diana Romero, the Abortion Access Delphi Project Panel, Roula AbiSamra, Kelly Baden, Nerys Benfield, Erin Berry, Kris Brandi, Lisley Canales, Jen Castle, Wendy Chavkin, Kamyon Conner, Jennifer Driver, Eve Espey, Marisa Falcon, Liza Fuentes, Kristina Gemzell‐Danielsson, Marlene Gerber Fried, Lawrence Gostin, Lorie Harper, Lisa H. Harris, Asha Hassan, Mashayla Hays, Kwajelyn J. Jackson, Shivana Jorawar, Farzana Kapadia, Natalie Kapp, Kimberly Kelly, Camille Kidd, Hazar Khidir, Rachael Lorenzo, Jodi Magee, Terry McGovern, Colleen McNicholas, Margaret Montoya, Angela Moreno, Heidi Moseson, Alison Norris, Judy Norsigian, Lynn Paltrow, Isra Pananon Weeks, Maria A. Phillis, Rebecca B. Reingold, Whitney S. Rice, Dorothy E. Roberts, Lynn Roberts, Blake Rocap, DeShawn Taylor, Mishka Terplan, Terri‐Ann Thompson, Lin‐Fan Wang, Indra Wood Lusero, Nikki Zite   +54 more
wiley   +1 more source

Monocyte/macrophages may exert prominent roles in macrophage activation syndrome

Annals of Hematology
Secondary Hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening complication mostly occurs in adult patients with rheumatic disease, infection or lymphoma. To adequately steer treatment, clear discrimination of sHLH entities is essential.
Dongfei Yin, Jingshi Wang, Zhao Wang
doaj   +1 more source