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HMG CoA Reductase Inhibitors

Drugs, 1988
Lovastatin and simvastatin are the 2 best-known members of the class of hypolipidaemic agents known as HMG CoA reductase inhibitors. Clinical experience with lovastatin includes over 5000 patients, 700 of whom have been treated for 2 years or more, and experience with simvastatin includes over 3500 patients, of whom 350 have been treated for 18 months ...
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HMG CoA reductase inhibitors

Current Opinion in Lipidology, 1992
HMG CoA (β-hydroxy-β-methylglutaryl coenzyme A) reductase inhibitors are very effective in lowering total and low-density lipoprotein cholesterol. The incidence of adverse effects is very low with elevated transaminase levels and myopathy being of greatest concern.
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HMG‐CoA‐Reductase Inhibitors

Reactions Weekly, 2008
Mogens Lytken Larsen, Erik Berg Schmidt
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HMG-CoA reductase

Science-Business eXchange, 2010
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Bile acid derived HMG-CoA reductase inhibitors

Biochimica Et Biophysica Acta - Molecular Basis of Disease, 1994
Werner Kramer, G Wess, Alfons Enhsen
exaly  

Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

Nature Reviews Drug Discovery, 2003
Jonathan A Tobert
exaly  

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