Results 141 to 150 of about 29,559 (185)
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Regulation of HMG‐CoA reductase expression by hypoxia

Journal of Cellular Biochemistry, 2008
AbstractThe ability to maintain O2 homeostasis is essential to the survival of all invertebrate and vertebrate species. The transcriptional factor, hypoxia inducible factor 1 (HIF‐1), is the principal regulator of oxygen homeostasis. Under hypoxic condition HIF‐1 induces the transcription of several hypoxia‐responsive genes by binding to hypoxia ...
PALLOTTINI, V.   +6 more
openaire   +6 more sources

HMG CoA reductase inhibitors

Current Opinion in Lipidology, 1992
HMG CoA (β-hydroxy-β-methylglutaryl coenzyme A) reductase inhibitors are very effective in lowering total and low-density lipoprotein cholesterol. The incidence of adverse effects is very low with elevated transaminase levels and myopathy being of greatest concern.
SMITH ROBERT L   +7 more
openaire   +5 more sources

HMG CoA Reductase Inhibitors

Drugs, 1988
Lovastatin and simvastatin are the 2 best-known members of the class of hypolipidaemic agents known as HMG CoA reductase inhibitors. Clinical experience with lovastatin includes over 5000 patients, 700 of whom have been treated for 2 years or more, and experience with simvastatin includes over 3500 patients, of whom 350 have been treated for 18 months ...
openaire   +2 more sources

HMG CoA reductase inhibitors

Reactions Weekly, 2006
KUMAR YATENDRA   +7 more
  +5 more sources

HMG‐CoA‐Reductase Inhibitors

Reactions Weekly, 2008
Mogens Lytken Larsen, Erik Berg Schmidt
openaire   +2 more sources

Monitoring the Cellular Effects of HMG-CoA Reductase Inhibitors In Vitro and Ex Vivo

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
Iwona Cicha   +2 more
exaly  

HMG-CoA reductase

Science-Business eXchange, 2010
openaire   +1 more source

NK-104: a novel synthetic HMG-CoA reductase inhibitor

Expert Opinion on Investigational Drugs, 2000
Kouji Kajinami
exaly  

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