Results 181 to 190 of about 57,220 (227)
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Current Opinion in Lipidology, 1992
HMG CoA (β-hydroxy-β-methylglutaryl coenzyme A) reductase inhibitors are very effective in lowering total and low-density lipoprotein cholesterol. The incidence of adverse effects is very low with elevated transaminase levels and myopathy being of greatest concern.
M J Ashton, G Fenton
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HMG CoA (β-hydroxy-β-methylglutaryl coenzyme A) reductase inhibitors are very effective in lowering total and low-density lipoprotein cholesterol. The incidence of adverse effects is very low with elevated transaminase levels and myopathy being of greatest concern.
M J Ashton, G Fenton
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Regulation of HMG-CoA Reductase
1976Publisher Summary This chapter discusses the regulation of HMG-CoA reductase, which catalyzes the rate-limiting reaction of hepatic sterol synthesis. Both mitochondrial and extramitochondrial forms of acetoacetyl-CoA thiolase and the HMG-CoA synthase are present in liver tissue.
V W, Rodwell +2 more
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Drugs, 1988
Lovastatin and simvastatin are the 2 best-known members of the class of hypolipidaemic agents known as HMG CoA reductase inhibitors. Clinical experience with lovastatin includes over 5000 patients, 700 of whom have been treated for 2 years or more, and experience with simvastatin includes over 3500 patients, of whom 350 have been treated for 18 months ...
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Lovastatin and simvastatin are the 2 best-known members of the class of hypolipidaemic agents known as HMG CoA reductase inhibitors. Clinical experience with lovastatin includes over 5000 patients, 700 of whom have been treated for 2 years or more, and experience with simvastatin includes over 3500 patients, of whom 350 have been treated for 18 months ...
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2002
List of contributors. Preface. Stefano Bellosta, Rodolpho Paoletti, Alberto Corsini: History and development of HMG-CoA reductase inhibitors. Margaret E. Brousseau and Ernst J. Schafer: Structure and mechanisms of action of HMG-CoA reductase inhibitors.
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List of contributors. Preface. Stefano Bellosta, Rodolpho Paoletti, Alberto Corsini: History and development of HMG-CoA reductase inhibitors. Margaret E. Brousseau and Ernst J. Schafer: Structure and mechanisms of action of HMG-CoA reductase inhibitors.
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Proteopedia entry: HMG‐CoA reductase
Biochemistry and Molecular Biology Education, 2011openaire +2 more sources
HMG CoA reductase inhibitor (statin) and aortic valve calcium
Lancet, The, 2002Matthew J Budoff
exaly