Results 81 to 90 of about 29,559 (185)

Regulation of cholesterol biosynthesis and esterification by 25-hydroxycholesterol in a macrophage-like cell line: uncoupling by progesterone.

Journal of Lipid Research, 1984
The coordinated control of cholesterol biosynthesis and esterification by 25-hydroxycholesterol was studied in the macrophage-like cell line P388D1. Since 25-hydroxycholesterol rapidly stimulated incorporation of [3H]oleate into the cholesteryl ester ...
S C Miller, G Melnykovych
doaj   +1 more source

Metformin Partially Attenuates Simvastatin‐Induced Myotoxic Responses in C2C12 Myotubes Through Metabolic Adaptation

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He, Mike Wesselink, Jelle Y. Huijts, Zhenjia Zhong, Moritz Eggelbusch, Richard T. Jaspers, Rob C. I. Wüst   +6 more
wiley   +1 more source

Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors. [PDF]

ACS Omega, 2023
Samizo S, Kaneko H.
europepmc   +1 more source

HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia

Drug Design, Development and Therapy, 2015
Gunasekaran Baskaran,1 Shamala Salvamani,1 Siti Aqlima Ahmad,1 Noor Azmi Shaharuddin,1 Parveen Devi Pattiram,2 Mohd Yunus Shukor1 1Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, 2Department of Food Technology ...
Baskaran G, Salvamani S, Ahmad SA, Shaharuddin NA, Pattiram PD, Shukor MY   +5 more
doaj  

HMG-CoA reductase [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

HMG-CoA Reductase Inhibitors for Traumatic Brain Injury. [PDF]

Neurotherapeutics, 2023
Katlowitz K, Gopinath S, Cruz Navarro J, Robertson C.   +3 more
europepmc   +1 more source

Eupatilin Alleviates Hyperlipidemia in Mice by Inhibiting HMG-CoA Reductase. [PDF]

Biochem Res Int, 2023
Kim KJ, Kang NE, Oh YS, Jang SE.
europepmc   +1 more source

Natural products as HMG-CoA reductase inhibitors (statins) for the management of non-communicable diseases. [PDF]

Inflammopharmacology
Muhammad RN, Aborehab NM, Aly SH, Nasr NN, Hindam MO, Mustafa AM, Faheem SA, Fawzy MH, Abo-El Fetoh ME, El-Dessouki AM, Rabie MA, El-Shiekh RA, Youssef ME.   +12 more
europepmc   +1 more source

Post-Translational Regulation of HMG CoA Reductase. [PDF]

Cold Spring Harb Perspect Biol, 2022
Jo Y, DeBose-Boyd RA.
europepmc   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG-CoA Reductase for Coronary Artery Disease Treatment. [PDF]

ChemistryOpen
Mtulo YB, Deogratias G, Mgaya JE, Paluch AS, Paul L.   +4 more
europepmc   +1 more source