Results 91 to 100 of about 36,764 (181)

Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance. [PDF]

Antibiotics (Basel), 2023
Schelz Z, Muddather HF, Zupkó I.
europepmc   +1 more source

Computational identification of epifriedelanol and derived analogs from Mikania cordata as potential HMG-CoA reductase inhibitors. [PDF]

PLoS One
Banu M, Ahmed SS, Begum M, Rahman MO.
europepmc   +1 more source

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis. [PDF]

Cochrane Database Syst Rev, 2023
Tunnicliffe DJ, Palmer SC, Cashmore BA, Saglimbene VM, Krishnasamy R, Lambert K, Johnson DW, Craig JC, Strippoli GF.   +8 more
europepmc   +1 more source

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG-CoA) Reductase Negative Statin-Induced Necrotizing Myopathy: A Challenging Case. [PDF]

Cureus
Kaiteris AS, Tripathi R, Ayob G, Ng B.
europepmc   +1 more source

Computational Study of Base-Catalyzed Thiohemiacetal Decomposition in Pseudomonas mevalonii HMG-CoA Reductase. [PDF]

J Phys Chem B, 2023
Patel HN, Haines BE, Stauffacher CV, Helquist P, Wiest O.   +4 more
europepmc   +1 more source

Chronic Anti-HMG-CoA Reductase Positive Necrotizing Myositis With Remote Exposure to Statins. [PDF]

Cureus, 2023
Salar T, Jimenez M, Hameed M, Ocon A.
europepmc   +1 more source

HMG-CoA Reductase Inhibitors Suppress High Glucose-induced Excessive O2⁻ production in J-774 Cells

, 2003
Statins (HMG-CoA reductase inhibitors) have so-called pleiotropic effects, which directly reduce neoinitial inflammation of atherosclerosis, and one possible mechanism is the attenuation of oxidative stress.
Kase, Hiroyuki, Sato, Noriyuki, Kawagoe, Yoshiaki, Kato, Tetsuya, Suzuki, Manabu   +4 more
core  

HMG-CoA reductase inhibition preserves testicular function after torsion/detorsion by modulating oxidative stress and AKT signaling. [PDF]

Sci Rep
Yıldırım B, Baygül O, Şengün N, Üstündağ ÜV, Ateş N, Balçıkanlı Z, Beker MÇ, Keskin İ, Kılıç E.   +8 more
europepmc   +1 more source

Co-existing phaeochromocytoma and anti-HMG-CoA reductase immune-mediated necrotising myositis: a diagnostic challenge. [PDF]

Endocrinol Diabetes Metab Case Rep
Maher S, Lonergan E, Fullam S, O'Riordan B, Prichard R, Heffernan E, Connolly S, Orr C, Crowley RK.   +8 more
europepmc   +1 more source

d-β-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells

, 2010
Background: The rate-limiting enzyme of the mevalonate pathway, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, provides essential intermediates for the prenylation or dolichylation of growth-related proteins.
Mo, Huanbiao, Guntipalli, Praveen K., Fernandes, Nicolle V.   +2 more
core