Results 101 to 110 of about 200,536 (178)

Regulation of cholesterol biosynthesis and esterification by 25-hydroxycholesterol in a macrophage-like cell line: uncoupling by progesterone.

open access: yesJournal of Lipid Research, 1984
The coordinated control of cholesterol biosynthesis and esterification by 25-hydroxycholesterol was studied in the macrophage-like cell line P388D1. Since 25-hydroxycholesterol rapidly stimulated incorporation of [3H]oleate into the cholesteryl ester ...
S C Miller, G Melnykovych
doaj   +1 more source

Molecular Docking Kandungan Senyawa Biji Pepaya (Carica Papaya L.) Terhadap Enzim Hmg-Coa Reductase Sebagai Antihiperkolesterolemia [PDF]

open access: yes, 2018
Biji pepaya (Carica papaya L.) memiliki beberapa kandungan senyawa yang diduga memiliki efek penurunan kadar kolesterol dengan mekanisme sebagai penghambat enzim HMG-CoA reductase.
Hariyanti, Hariyanti   +2 more
core  

Uji potensi ekstrak etanol daun salam (syzygium polyanthum) hasil perkolasi terhadap aktivitas inhibisi enzim hmg-coa reductase secara in vitro [PDF]

open access: yes, 2018
Daun Salam (Syzygium polyanthum) dikenal memiliki aktivitas antikolesterol. Daun salam banyak diteliti secara in vivo dalam menurunkan kolesterol, namun belum ada informasi ilmiah mengenai mekanisme kerja inhibisi enzim HMG-CoA Reductase dari ekstrak ...
Yonas, Stefania Maureen Kasih
core  

HMG-CoA Reductase inhibitors: an updated review of patents of novel compounds and formulations (2011-2015)

open access: yes, 2016
Introduction: Statins are remarkably safe and efficient medications that are the mainstay of hypercholesterolemia treatment and have proven to be an invaluable tool to lower the risk of acute cardiovascular events.
Maria João Ramos (47524)   +7 more
core   +1 more source

MTD-comsia modelling of HMG-CoA reductase inhibitors

open access: yes, 2011
The 3D quantitative structure-activity relationship for a series of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors based on the pyrrolylethyl-tetrahydropyranone scaffold was examined using the Minimal Topological Difference (MTD ...
Corina Duda-Seiman   +6 more
core   +1 more source

HMG-CoA reductase 활성과 장내 미생물 생육에 대한 플라보노이드의 영향

open access: yes, 2003
Thesis (master`s)--서울대학교 대학원 :농생명공학부,2003.The effects of flavonoids an inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which is rate limiting enzyme in cholesterol biosynthesis, and growth-inhibition of intestinal microflora ...
전구주
core  

MTD–CoMSIA modelling of HMG-CoA reductase inhibitors [PDF]

open access: yes, 2010
The 3D quantitative structure–activity relationship for a series of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors based on the pyrrolylethyl-tetrahydropyranone scaffold was examined using the Minimal Topological Difference (MTD) method and ...
VALENTIN CAREJA   +6 more
core   +1 more source

Pityriasis Lichenoides Chronica Associated with Use of HMG-CoA Reductase Inhibitors

open access: yes, 2012
Herein, we present three cases of Pityriasis lichenoides chronica (PLC) in patients who developed the rash after use of 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitors.
• RJB Massay, AA Maynard
core  

SCREENING OF HMG CO A REDUCTASE INHIBITOR PRODUCING MARINE ACTINOMYCETES [PDF]

open access: yes, 2013
The objective of the present study was screening of 3-hydroxy-3- methyl glutaryl Co A (HMG CoA) reductase inhibitor producing marine actinomycetes.
SRILAKSHMI, SANKAR, PRABHAKAR,LAKSHMINARAYANA, SRINU, PHANI BHUSHAN,MOGES,
core  

Pseudomonas mevalonii HMG-CoA reductase: Transcriptional regulation and identification of a glutamate essential for catalysis

open access: yes, 1990
Pseudomonas mevalonii HMG-CoA reductase (E.C. 1.1.1.38) is induced in cells grown on mevalonate (J. F. Gill, Jr., M. J. Beach, and V. W. Rodwell, J. Bacteriol. 160, 294-298, 1984), and the mvaA gene, which encodes P. mevalonii HMG-CoA reductase, has been
Wang, Yuli
core   +1 more source

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