Results 121 to 130 of about 2,248 (159)

HMG1 and 2: “architectural” DNA-binding proteins

Biochemical Society Transactions, 2001
HMG1 and 2 (high mobility group proteins 1 and 2; renamed HMGB1 and 2) contain two DNA-binding HMG-box domains (A and B) and a long acidic C-terminal domain. They bind DNA without sequence specificity, but have a high affinity for bent or distorted DNA, and bend linear DNA.
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Mapping of the Hmg1 gene and of seven related sequences in the mouse

Mammalian Genome, 1995
The High Mobility Group 1 protein (HMG1) is an abundant and highly conserved chromosomal protein. Mouse HMG1 is encoded by the Hmg1 gene, containing four introns, but the murine genome contains many related sequences that are mostly retrotransposed pseudogenes. By using an interspecific cross, we have mapped the functional Hmg1 gene on mouse Chromosome
Gariboldi, M, De Gregorio, L, Ferrari, S, Manenti, G, Pierotti, M A, Bianchi, M E, Dragani, T A   +6 more
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Prokaryotic HU and eukaryotic HMG1: a kinked relationship

Molecular Microbiology, 1994
SummaryHU and IHF proteins have long been considered the prokaryotic analogues of eukaryotic histones. Their ability to bend DNA, however, is distinctly similar to that of eukaryotic HMG‐box proteins, a recently identified family of chromatin components and transcription factors.
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Identification of the core-histone-binding domains of HMG1 and HMG2

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1986
High mobility group (HMG) nonhistone chromosomal proteins are a group of abundant, conservative and highly charged nuclear proteins whose physiological role in chromatin is still unknown. To gain insight into the interactions of HMG1 and HMG2 with the fundamental components of chromatin we have introduced the methodology of photochemical crosslinking ...
J, Bernués, E, Espel, E, Querol
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HMG1 and HU proteins: architectural elements in plant chromatin

Trends in Plant Science, 1998
Abstract Specific deformation of the double helix is often necessary for activity involving DNA, but the inflexibility of naked DNA means that proteins are needed to achieve this deformation. Complex nucleoprotein structures are formed, and the synergistic action of proteins within these complexes provides the necessary precision required for the ...
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The Role of HMG1 Protein in Nucleosome Assembly and in Chromatin Replication

1984
Much progress has been made in understanding the basic structure of chromatin, at least at the nucleosomal level. But, how the eukaryotic DNA is folded into this structure, changes its shape and unfolds is still unknown.
C, Bonne-Andrea, F, Harper, J, Sobczak, A M, De Recondo   +3 more
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Structure of genes encoding chromosomal HMG1 proteins from maize

Gene, 1999
The high mobility group (HMG) proteins of the HMG1 family are architectural proteins in chromatin that are considered to facilitate the formation of complex nucleoprotein structures in various biological processes such as transcription and recombination. Plants express a variety of these non-sequence-specific DNA-bending proteins.
Krech, A. B., Wurz, A., Stemmer, C., Feix, G., Grasser, Klaus D.   +4 more
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Linker Histones and HMG1 Proteins of Higher Plants

Plant Biology, 2000
Abstract: Linker histones and the proteins belonging to the high mobility group 1 (HMG1) family are the most abundant proteins associated with the internucleosomal linker DNA in eukaryotic chromatin. Despite their relative abundance, there are indications that they may be involved in specific developmental pathways.
Jerzmanowski, A., Przewloka, M., Grasser, Klaus D.   +2 more
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[HMG1 domains: the victims of circumstance].

Molekuliarnaia biologiia, 2002
The method of circular dichroism (CD) was used to compare DNA behavior during its interaction with linker histone H1 and with non-histone chromosomal protein HMG1 at different ionic strength and at different protein content in the system. The role of negatively charged C-terminal fragment of HMG1 was analyzed using recombinant protein HMG1-(A + B ...
E V, Chikhirzhina, A M, Polianichko, A N, Skvortsov, E I, Kostyleva, C, Houssier, V I, Vorob'ev   +5 more
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Mapping and molecular characterization of five HMG1-related DNA sequences

Cytogenetic and Genome Research, 1998
Recently, the high mobility group (HMG) proteins have attracted a lot of interest since it was shown that some members of that group can causally be involved in tumorigenesis. One HMG protein gene member is HMG1 for which the number of related DNA sequences has been estimated to be approximately 20–30.
P, Rogalla, Z, Borda, K, Meyer-Bolte, K H, Tran, S, Hauke, R, Nimzyk, J, Bullerdiek   +6 more
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