Results 141 to 150 of about 51,717 (306)

HMGB1 shRNA dowregulates IL6 secretion.

, 2013
HMGB1 mRNA expression or protein expression were assessed respectively by RT-PCR (A) or Western blot (B) after 12h in culture of stably SW872 infected with scrumble shRNA (Sh CTL) or HMGB1 shRNA (sh HMGB1) constructs.
Brice Nativel (461285), Maya Césari (461293), Thomas Iwema (2786), Philippe Gasque (331765), Jessica Andries (461289), Mery Marimoutou (461286), Manoj Kumar Gunasekaran (461288), Vincent G. Thon-Hon (461287), Giovédie Stanislas (461290), Christine Robert Da Silva (461292), Wildriss Viranaicken (347964), Cynthia Planesse (461291)   +11 more
core   +1 more source

Macrophage‐derived HMGB1 is dispensable for tissue fibrogenesis

, 2019
International audienceAlarmins and damage-associated molecular patterns (DAMPs) are powerful inflammatory mediators, capable of initiating and maintaining sterile inflammation during acute or chronic tissue injury.
Moreau, Elsa, Dray, Cedric, Branchereau, Maxime, Valet, Philippe, P., Riant, Elodie, Paccoud, Romain, Calise, Denis, Personnaz, Jean, Piccolo, Enzo, Pradère, Jean-Philippe, Filliol, Aveline, Heymes, Christophe, Gourdy, Pierre, Schwabe, Robert, F   +13 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Sequence alignment of Lj-HMGB1 with HMGB1/2/3 of other species using ClustalX.

, 2012
The accession numbers of the amino acid sequences extracted from the EXPASY database are as follows: human HMGB1 (P09429); mouse HMGB1 (P63158); chick HMGB1 (Q9PUK9); frog HMGB1 (Q7SZ42); human HMGB2 (P26583); mouse HMGB2 (P30681); chick HMGB2 (P26584 ...
Yue Pang (168110), Rong Xiao (130656), Qingwei Li (168118), Xin Liu (43569)   +3 more
core   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

C-terminal domain of nonhistone protein HMGB1 as a modulator of HMGB1–DNA structural interactions

, 2018
The HMGB1 protein (High Mobility Group protein 1) participates in the formation of functionally significant DNA-protein complexes. HMGB1 protein contains two DNA-binding domains and negatively charged C-terminal region.
Vorob'ev, V., Wieser, H., Chikhirzhina, E., Polyanichko, A., Leonenko, Z.   +4 more
core   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

High-Intensity Interval Training Decreases Circulating HMGB1 in Individuals with Insulin Resistance: Plasma Lipidomics Correlate with Associated Cardiometabolic Benefits

Frontiers in Bioscience-Landmark
Background: Bodyweight high-intensity interval training (BW-HIIT) is an effective, time-efficient exercise method that reduces cardiovascular risk factors and improves muscle endurance without requiring external equipment.
Gabriela Martinez Bravo, Prabu Paramasivam, Gabriella F. Bellissimo, Quiteria Jacquez, Huayu Zheng, Fabiano Amorim, Lara Kovell, Roberto Ivan Mota Alvidrez   +7 more
doaj   +1 more source