Results 131 to 140 of about 14,518 (216)

Anti-HMGCR Specificity of HALIP

A distinctive new indirect immunofluorescence pattern in liver tissue has been associated with anti-HMGCR autoantibodies. It is known as HALIP (HMGCR Associated Liver Immunofluorescence Pattern). In this study, we furthered the original studies to demonstrate the association of anti-HMGCR antibodies with the HALIP.
Baucells, Andrés||, Martínez, Maria Angeles||, Alvarado, Marcelo||, Mariscal, Anaís||, Martinez-Martinez, Laura||, Juarez, Candido||, Selva O'Callaghan, Albert||   +6 more
openaire   +1 more source

P097 A masquerading case of anti-HMGCR myopathy

Rheumatology Advances in Practice
Abstract Introduction Diseases of the muscle are called myopathies; diseases causing inflammation are termed myositis. Proximal muscle weakness, myalgia, weight loss and premature fatigue are common symptoms. The differential is broad.
Dosanjh, Gurdit, Cernovschi, Natalia, Pugh, Non Catherine   +2 more
openaire   +1 more source

Pathogenicity of autoantibodies anti-SRP and anti-HMGCR in autoimmune necrotizing myopathies

, 2017
Les myopathies auto-immunes (MAI), classiquement appelées myosites ou myopathies inflammatoires idiopathiques, représentent un groupe de maladies définies par des caractéristiques cliniques, histopathologiques et biologiques. Une des caractéristiques les
Bergua, Cecile
core  

HMGCR enzyme deficiency model in mice

HMGCR enzyme deficiency model in mice is used in the mitoHMGCR project to study the physiological role of HMGCR enzyme and molecular mechanisms of  statin-induced side effects.The specific objectives of the mitoHMGCR project cover delineation of detrimental effects of HMGCR deficiency in the tissue-specific KO mice models (liver and brain astrocyte ...
openaire   +2 more sources

Increasing recognition of statin-associated anti-HMGCR antibody-positive autoimmune myopathy: a single-center retrospective study. [PDF]

Clin Rheumatol
Mali M, Pirilä L, Jokela M, Pääkkö T, Mali M.   +4 more
europepmc   +1 more source

Leave-one-out plots in preliminary analysis of HMGCR and APOB-mediated lipid.

A. Leave-one-out plots of HMGCR-mediated LDL-C on RA (Okada Y); B. Leave-one-out plots of HMGCR-mediated LDL-C on RA (FINNGEN); C. Leave-one-out plots of APOB-mediated LDL-C on RA (Okada Y); D. Leave-one-out plots of APOB-mediated LDL-C on RA (FINNGEN). (
Zhican Huang (18071525), Haiyan Zhou (405123), Yutong Wu (3130584), Jin Yao (486694), Jun Zhu (84054), Xin Yang (104842), Li Cui (37567), Ting Cui (673336)   +7 more
core   +1 more source

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy With Subsequent Diagnosis of Mantle Cell Lymphoma. [PDF]

Cureus
Zhao C, Duffield A, Toz B.
europepmc   +1 more source

Etiopathogenesis of Immune-Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances. [PDF]

CNS Neurosci Ther
Gao C, Li W, Liu Q, Wang G, Peng Q.
europepmc   +1 more source

Anti-HMGCR Myopathy During NSTEMI Evaluation: The Statin Paradox and Troponin Trap. [PDF]

JACC Case Rep
Quasem K, Carrasquel-Alvarez M, Maser H, Russell C, Barker T, Thulluri R, Felice J, Nadipalli V, Shah I, Hong C.   +9 more
europepmc   +1 more source

HMGCR and PCSK9 variants and cardiovascular risk [PDF]

Nature Reviews Cardiology, 2016
openaire   +1 more source