Results 61 to 70 of about 41,460 (160)

Early Stage Development of a Newcastle Disease Vaccine Candidate in Corn

Frontiers in Veterinary Science, 2020
Newcastle disease (ND) is a viral disease that causes labored breathing, periorbital oedema, and ataxia in the majority of avian species. The available vaccines against Newcastle disease virus (NDV) are limited, owing to their low reactivity and multiple
Naila Shahid, Tahir Rehman Samiullah, Sana Shakoor, Ayesha Latif, Aneela Yasmeen, Saira Azam, Ahmad Ali Shahid, Tayyab Husnain, Abdul Qayyum Rao   +8 more
doaj   +1 more source

The haemagglutinin–neuraminidase protein of velogenic Newcastle disease virus enhances viral infection through NF-κB-mediated programmed cell death

Veterinary Research
The haemagglutinin–neuraminidase (HN) protein, a vital membrane glycoprotein, plays a pivotal role in the pathogenesis of Newcastle disease virus (NDV). Previously, we demonstrated that a mutation in the HN protein is essential for the enhanced virulence
Xiaolong Lu, Tiansong Zhan, Qiwen Zhou, Wenhao Yang, Kaituo Liu, Yu Chen, Ruyi Gao, Jiao Hu, Min Gu, Shunlin Hu, Xin-an Jiao, Xiaoquan Wang, Xiufan Liu, Xiaowen Liu   +13 more
doaj   +1 more source

Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein

Brazilian Journal of Infectious Diseases
A point mutation from guanine (G) to adenine (A) at nucleotide position 1081 in the hemagglutinin-neuraminidase (HN) gene has been associated with neurovirulence of Urabe AM9 mumps virus vaccine. This mutation corresponds to a glutamic acid (E) to lysine
Gerardo Santos-López, Thomas Scior, María del Tránsito Borraz-Argüello, Verónica Vallejo-Ruiz, Irma Herrera-Camacho, José Tapia-Ramírez, Julio Reyes-Leyva   +6 more
doaj   +1 more source

Characterization of genotype-specific epitopes of the HN protein of mumps virus.

Journal of General Virology, 1997
The SBL-1 strain of mumps virus, grouping with genotype A on the basis of the small hydrophobic protein gene sequence, was grown in the presence of three different monoclonal antibodies. The monoclonal antibodies were directed against the haemagglutinin-neuraminidase (HN) protein and they inhibited haemagglutinating activity and infectivity of the ...
C, Orvell, A R, Alsheikhly, M, Kalantari, B, Johansson   +3 more
openaire   +2 more sources

Molecular characterisation of Newcastle disease virus exotic isolate in East Java, Indonesia

Bulgarian Journal of Veterinary Medicine, 2021
Newcastle disease virus (NDV) is ssRNA paramyxovirus causing clinical signs, varying from subclinical infections to 100% mortality in infected chickens. Haemagglutinin-neuraminidase (HN) protein has an important role related to infection and pathogenesis,
N. Kusumarahayu, N. Putri, R. Ernawati, J. Rahmahani, S. Suwarno , F. A. Rantam   +5 more
doaj   +1 more source

Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein

Virology, 2008
The mechanism by which the paramyxovirus hemagglutinin-neuraminidase (HN) protein couples receptor binding to activation of virus entry remains to be fully understood, but the HN stalk is thought to play an important role in the process. We have characterized ectodomain constructs of the parainfluenza virus 5 HN to understand better the underlying ...
Yuan, Ping, Leser, George P., Demeler, Borries, Lamb, Robert A., Jardetzky, Theodore S.   +4 more
openaire   +2 more sources

In Vivo Production of HN Protein Increases the Protection Rates of a Minicircle DNA Vaccine against Genotype VII Newcastle Disease Virus. [PDF]

Vaccines (Basel), 2021
Wang Z, Zhao X, Wang Y, Sun C, Sun M, Gao X, Jia F, Shan C, Yang G, Wang J, Huang H, Shi C, Yang W, Qian A, Wang C, Jiang Y.   +15 more
europepmc   +1 more source

A novel chimpanzee adenovirus vector vaccine for protection against infectious bronchitis and Newcastle disease in chickens

Veterinary Research
The development of effective poultry vaccines is crucial for maintaining flock health and productivity. In this study, we developed and evaluated a recombinant chimpanzee adenovirus vaccine (PAD-S1-HN) that simultaneously expresses the infectious ...
Chengyao Hou, Ruiqi Ni, Lijun Zhao, Wenjun Yan, Kailu Wang, Qinyuan Chu, Xinggui Chen, Hongning Wang, Xin Yang   +8 more
doaj   +1 more source

Genomic insights into heterotrophic nitrifying-aerobic denitrifying bacteria from petroleum terminal effluents

Heliyon
Heterotrophic nitrification-aerobic denitrification (HN/AD) is a single-organism process that converts ammonia into nitrogen gas under strictly aerobic conditions, playing a crucial role in biological ammonia removal from industrial wastewater.
Lutecia Rigueira Medina, Lívia Carneiro Fidélis Silva, Helena Santiago Lima, Pedro Marcus Pereira Vidigal, Alex Gazolla de Castro, Maira de Paula Sousa, Rodrigo Suhett de Souza, Sérgio Oliveira de Paula, Cynthia Canêdo da Silva   +8 more
doaj   +1 more source

How a paramyxovirus fusion/entry complex adapts to escape a neutralizing antibody

Nature Communications
Paramyxoviruses including measles, Nipah, and parainfluenza viruses are public health threats with pandemic potential. Human parainfluenza virus type 3 (HPIV3) is a leading cause of illness in pediatric, older, and immunocompromised populations.
Tara C. Marcink, Gillian Zipursky, Elizabeth B. Sobolik, Kate Golub, Emily Herman, Kyle Stearns, Alexander L. Greninger, Matteo Porotto, Anne Moscona   +8 more
doaj   +1 more source