Serum Level of MVIH, HNF1A-AS1, and NEAT1 Long Noncoding RNAs: Potential Biomarkers for Colorectal Cancer. [PDF]
Asian Pac J Cancer PrevLong noncoding RNAs (lncRNAs) are a significant class of non-coding RNAs that play critical roles in cancer development, progression, and metastasis. This study aimed to investigate the expression of MVIH, HNF1A-AS1, and NEAT1 in the blood samples of patients with colorectal cancer (CRC), both before and three months after surgery, in comparison to a ...
Mohamadnejad M +7 more
europepmc +7 more sources
The lncRNA HNF1A‐AS1 is a negative prognostic factor and promotes tumorigenesis in osteosarcoma [PDF]
Journal of Cellular and Molecular Medicine, 2017 AbstractRecent studies have revealed that long noncoding RNA HNF1A‐antisense 1 (HNF1A‐AS1) plays an important role in the development of several human malignancy entities. However, the expression and function of HNF1A‐AS1 in the carcinogenesis and development of osteosarcoma remains unknown.
Lijun Cai, Zong-Ping Luo
exaly +5 more sources
Evaluation of Long Non-Coding RNAs: HNF1A-AS1 and MVIH Expressions and Their Clinical Significance in Human Gastric Cancer [PDF]
Journal of Genetic Resources, 2020 Gastric cancer is one of the most common cancers in the world. Late diagnosis is the main cause of the high rate of treatment failure and death among patients with gastric cancer; therefore identifying the molecular basis of cancer initiation and ...
Hasan Rahimi-Tamandegani +2 more
doaj +2 more sources
Long non-coding RNA HNF1A-AS1 promotes proliferation and suppresses apoptosis of bladder cancer cells through upregulating Bcl-2. [PDF]
Oncotarget, 2017 Emerging evidences have indicated that long non-coding RNAs (lncRNAs) are pivotal regulators of tumor development and progression. HNF1A-AS1 (HNF1A antisense RNA 1, C12 or f27) is a novel long non-coding RNA that acts as a potential biomarker and is involved in development and progression of several cancers.
Zhan Y +10 more
europepmc +6 more sources
Hnf1aos1 as a Metabolic Coordinator of Hepatic Lipid Homeostasis and Feedback Control [PDF]
Non-Coding RNABackground: Long noncoding RNAs (lncRNAs) have emerged as critical regulators of hepatic metabolism and disease progression. The hepatocyte nuclear factor 1 alpha antisense 1 (HNF1A-AS1) lncRNA modulates liver-specific transcription factors; however, its
Beshoy Armanios +7 more
doaj +2 more sources
Unraveling the Regulatory Impact of LncRNA Hnf1aos1 on Hepatic Homeostasis in Mice [PDF]
Non-Coding RNABackground/Objectives: Long non-coding RNAs (lncRNAs) play significant roles in tissue development and disease progression and have emerged as crucial regulators of gene expression.
Beshoy Armanios +6 more
doaj +2 more sources
Mechanistic roles of long non-coding RNAs in gastric cancer therapy resistance [PDF]
Non-coding RNA ResearchGastric cancer (GC) remains a leading cause of cancer-related mortality worldwide. While gastrointestinal tumor screening has reduced incidence and mortality, its treatment faces is hindered by challenges including chemotherapy resistance and poor ...
Jiayi Chen, Juanmei Gao
doaj +2 more sources
A LncRNA panel within EpCAM-specific exosomes for noninvasive early diagnosing non-small cell lung cancer [PDF]
Respiratory ResearchBackground Plasma tumor-associated exosomes represent a promising source for cancer biomarkers; however, the role of long non-coding RNAs (lncRNAs) within these exosomes is not well-defined in non-small cell lung cancer (NSCLC).
Linyuan Liu +9 more
doaj +2 more sources
Revealing new associations between lncRNAs and diseases through cross attention mechanism and multiple level feature fusion [PDF]
Scientific ReportsRevealing new lncRNA-disease associations (LDAs) is necessary to decipher pathological mechanisms and find new clues of diagnosis and therapy for complex diseases. However, experimental methods for LDA identification need a significant amount of time and
Xueming Luo +3 more
doaj +2 more sources
Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal cancer [PDF]
Frontiers in ImmunologyObjectiveEsophageal cancer (EC) is characterized by a high degree of malignancy and poor prognosis. N6-methyladenosine (m6A), a prominent post-transcriptional modification of mRNA in mammalian cells, plays a pivotal role in regulating various cellular ...
Ming Zhang +9 more
doaj +2 more sources