Unraveling the Regulatory Impact of LncRNA Hnf1aos1 on Hepatic Homeostasis in Mice [PDF]
Non-Coding RNABackground/Objectives: Long non-coding RNAs (lncRNAs) play significant roles in tissue development and disease progression and have emerged as crucial regulators of gene expression.
Beshoy Armanios +6 more
doaj +3 more sources
Diagnostics, 2022 Long non-coding ribonucleic acids (LncRNAs) are recently known for their role in regulating gene expression and the development of cancer. Controversial results indicate a correlation between the tissue expression of LncRNA and LncRNA content of ...
Samaneh Talebi +10 more
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Expression analysis of NF-ƙB-related long non-coding RNAs in bipolar disorder
Scientific Reports, 2022 Bipolar disorder (BD) is a mental disorder that leads to abnormal swings in mood, energy, activity level, attention, and the capability to accomplish daily tasks. Several long non-coding RNAs (lncRNAs) are dysregulated in BD patients.
Sara Ahmadi Teshnizi +7 more
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Long non-coding RNAs as molecular links and circulating biomarkers between type 2 diabetes and colorectal cancer: focus on shared signaling pathways, epigenetic regulation, and ubiquitination mechanisms [PDF]
Frontiers in Molecular BiosciencesType 2 Diabetes (T2D) and Colorectal Cancer (CRC) share a complex bidirectional relationship driven by common metabolic and inflammatory pathways. This review comprehensively examines the pivotal role of Long Non-Coding RNAs (lncRNAs) as molecular ...
Lang Wu, Qing Meng, Yang Zhou
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Hnf1aos1 as a Metabolic Coordinator of Hepatic Lipid Homeostasis and Feedback Control [PDF]
Non-Coding RNABackground: Long noncoding RNAs (lncRNAs) have emerged as critical regulators of hepatic metabolism and disease progression. The hepatocyte nuclear factor 1 alpha antisense 1 (HNF1A-AS1) lncRNA modulates liver-specific transcription factors; however, its
Beshoy Armanios +7 more
doaj +2 more sources
Mechanistic roles of long non-coding RNAs in gastric cancer therapy resistance [PDF]
Non-coding RNA ResearchGastric cancer (GC) remains a leading cause of cancer-related mortality worldwide. While gastrointestinal tumor screening has reduced incidence and mortality, its treatment faces is hindered by challenges including chemotherapy resistance and poor ...
Jiayi Chen, Juanmei Gao
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A LncRNA panel within EpCAM-specific exosomes for noninvasive early diagnosing non-small cell lung cancer [PDF]
Respiratory ResearchBackground Plasma tumor-associated exosomes represent a promising source for cancer biomarkers; however, the role of long non-coding RNAs (lncRNAs) within these exosomes is not well-defined in non-small cell lung cancer (NSCLC).
Linyuan Liu +9 more
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Revealing new associations between lncRNAs and diseases through cross attention mechanism and multiple level feature fusion [PDF]
Scientific ReportsRevealing new lncRNA-disease associations (LDAs) is necessary to decipher pathological mechanisms and find new clues of diagnosis and therapy for complex diseases. However, experimental methods for LDA identification need a significant amount of time and
Xueming Luo +3 more
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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal cancer [PDF]
Frontiers in ImmunologyObjectiveEsophageal cancer (EC) is characterized by a high degree of malignancy and poor prognosis. N6-methyladenosine (m6A), a prominent post-transcriptional modification of mRNA in mammalian cells, plays a pivotal role in regulating various cellular ...
Ming Zhang +9 more
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Serum Level of MVIH, HNF1A-AS1, and NEAT1 Long Noncoding RNAs: Potential Biomarkers for Colorectal Cancer. [PDF]
Asian Pac J Cancer PrevLong noncoding RNAs (lncRNAs) are a significant class of non-coding RNAs that play critical roles in cancer development, progression, and metastasis. This study aimed to investigate the expression of MVIH, HNF1A-AS1, and NEAT1 in the blood samples of ...
Mohamadnejad M +7 more
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