Results 31 to 40 of about 11,404 (127)

Genetic and Epigenetic Association of Hepatocyte Nuclear Factor-1α with Glycosylation in Post-Traumatic Stress Disorder

, 2022
Post-traumatic stress disorder (PTSD) is a complex trauma-related disorder, the etiology and underlying molecular mechanisms of which are still unclear and probably involve different (epi)genetic and environmental factors.
Tudor, Lucija, Kozumplik, Oliver, Nela Pivac, Zoldos, Vlatka, Pivac, Nela, Suzana Uzun, Dubravka Svob Strac, Lucija Tudor, Vlatka Zoldos, Konjevod, Marcela, Oliver Kozumplik, Svob Strac, Dubravka, Nedic Erjavec, Gordana, Gordan Lauc, Uzun, Suzana, Matea Nikolac Perkovic, Nikolac Perkovic, Matea, Gordana Nedic Erjavec, Marcela Konjevod, Lauc, Gordan   +19 more
core   +1 more source

HNF1a-induced promoter activities of Akr1c12 and 13 in HEK293 cells.

, 2021
HEK293 cells were co-transfected with HNF1a and luciferase reporter construct containing Akr1c12 (-1115 to -1) or Akr1c13 (-1006 to -1) promoter region. All values represent mean ± SEM. (PDF)
Domenico Accili (185429), Jinsook Son (11766939), Yasutaka Miyachi (3178986), Taiyi Kuo (2863205)   +3 more
core   +1 more source

Exploring the Regulation of Jiangtang Tiaozhi Formula on the Biological Network of Obese T2DM Complicated With Dyslipidemia Based on Clinical Transcriptomics

Frontiers in Endocrinology, 2022
ObjectiveTo use systems biology to explore the biomolecular network mechanism of the Jiangtang Tiaozhi Recipe (JTTZR) in the intervention of obese Type 2 diabetes (T2DM) patients with dyslipidemia.MethodsTwelve patients with obese type 2 diabetes ...
Tingting Bao, Tingting Bao, Song Wang, Song Wang, Yingying Yang, Yingying Yang, Lisha He, Lin Han, Tiangang Zhai, Tiangang Zhai, Jia Chen, Qiang Zhou, Xiyan Zhao, Fengmei Lian, Linhua Zhao, Xiaolin Tong   +15 more
doaj   +1 more source

Screen and identification of BVES-AS1-201-50aa.

, 2023
(A) Venn diagram showed the lncRNAs that are aberrant expression in CRC, are associated with poor prognosis of CRC patients, and are predicted to have encoding potential.
Weiwei Zheng (140828), Yucheng Song (14231285), Yingchang Guo (16425979), Guangtan Zhang (16425982), Xuebin Bao (16425988), Junwei Bai (9730322), Xiaofei Song (3111648), Qinhui Zhu (16425985), Chao Zhang (51048), Gang Wu (23885)   +9 more
core   +1 more source

Hepatic nuclear factor-1A (HNF1A) antisense long non-coding RNA subcellular location and function [PDF]

, 2021
The human and mouse hepatocyte nuclear factor 1 homeobox A (HNF1A) gene locus expresses the HNF1A transcript and a long non-coding RNA in the antisense (HNF1A-AS1) direction. HNF1A-AS1 is expressed in numerous types of cancers.
Sepehri, Zahra
core  

HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A [PDF]

, 2022
The biological purpose of long non-coding RNAs (lncRNAs) is poorly understood. Haploinsufficient mutations in HNF1A homeobox A (HNF1A), encoding a homeodomain transcription factor, cause diabetes mellitus.
Vas, Matías G. de, Gonzalez-Franco, Roser, Heyn, Holger, Ravassard, Philppe, Balboa, Diego, Garcia-Hurtado, Javier, De Vas, Matías G, Gonzalez Franco, Roser, Beucher, Anthony, Bernal, Aina, Miguel-Escalada, Irene, Vargiu, Pierfrancesco, De Vas, Matías G., Angel Maestro, Miguel, Miguel Escalada, Irene, De Vas, Matias, Maestro, Miguel Angel, Ferrer, Jorge, Ravassard, Philippe, Ortega, Sagrario   +19 more
core   +1 more source

The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.

, 2023
The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.
Weiwei Zheng (140828), Yucheng Song (14231285), Yingchang Guo (16425979), Guangtan Zhang (16425982), Xuebin Bao (16425988), Junwei Bai (9730322), Xiaofei Song (3111648), Qinhui Zhu (16425985), Chao Zhang (51048), Gang Wu (23885)   +9 more
core   +1 more source

Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease

JCI Insight, 2023
Ulcerative colitis (UC), Crohn’s disease (CD), and celiac disease are prevalent intestinal inflammatory disorders with nonsatisfactory therapeutic interventions.
Tzipi Braun, Katya E. Sosnovski, Amnon Amir, Marina BenShoshan, Kelli L. VanDussen, Rebekah Karns, Nina Levhar, Haya Abbas-Egbariya, Rotem Hadar, Gilat Efroni, David Castel, Camila Avivi, Michael J. Rosen, Anne M. Grifiths, Thomas D. Walters, David R. Mack, Brendan M. Boyle, Syed Asad Ali, Sean R. Moore, Melanie Schirmer, Ramnik J. Xavier, Subra Kugathasan, Anil G. Jegga, Batya Weiss, Chen Mayer, Iris Barshack, Shomron Ben-Horin, Igor Ulitsky, Anthony Beucher, Jorge Ferrer, Jeffrey S. Hyams, Lee A. Denson, Yael Haberman   +32 more
doaj   +1 more source

Novel Loss-of-Function Variant in HNF1a Induces β-Cell Dysfunction through Endoplasmic Reticulum Stress

, 2022
Heterozygous variants in the hepatocyte nuclear factor 1a (HNF1a) cause MODY3 (maturity-onset diabetes of the young, type 3). In this study, we found a case of novel HNF1a p.Gln125* (HNF1a-Q125ter) variant clinically.
Yuxian Zhang, Zhao, Qing, Zhang, Yuxian, Li, Xuejun, Huang, Caoxin, Likun Wang, Wang, Likun, Qing Zhao, Xuejun Li, Mingyu Li, Chen, Yinling, Juanjuan Tian, Huang, Bingkun, Jianxin Jia, Jia, Jianxin, Yinling Chen, Li, Mingyu, Caoxin Huang, Tian, Juanjuan, Bingkun Huang   +19 more
core   +1 more source

Figure S1, Figure S2 and Table S1 from EGR1-Mediated Transcription of lncRNA-HNF1A-AS1 Promotes Cell-Cycle Progression in Gastric Cancer

, 2018
Figure S1 showed that the overexpression and knockdown efficiency of HNF1A-AS1 in both GC cells and the proliferation of GC cells transfected with SI-HNF1A-AS1-2 were inhibited.
Peng Gao (35465), Hai-Ting Liu (9083636), Ran-Ran Ma (6468101), Sen Liu (438456), Lei Liu (5074)   +4 more
core   +1 more source