Results 71 to 80 of about 9,918 (148)
Aging Cell, Volume 25, Issue 6, June 2026.iLDA‐SGCN integrates singular value decomposition and dual graph convolutional networks to predict lncRNA‐disease associations. It achieves superior performance on two benchmark datasets and identifies 33 candidate lncRNAs across 8 age‐related diseases.
Yu Guo +8 more
wiley +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
Metamorphosis and lncRNAs: A Close Relationship
genesis, Volume 64, Issue 2, April 2026.ABSTRACT The classical definition of metamorphosis is a post‐embryonic transformation, such as from a tadpole to a froglet. However, recent studies suggest this process occurs to some degree in all vertebrates, as the underlying endocrine and molecular pathways are highly conserved. With the advent of high‐throughput sequencing, transcriptomic data for
H. Herrera‐Orozco +1 more
wiley +1 more source
Hepatic nuclear factor-1A (HNF1A) antisense long non-coding RNA subcellular location and function
, 2021 The human and mouse hepatocyte nuclear factor 1 homeobox A (HNF1A) gene locus expresses the HNF1A transcript and a long non-coding RNA in the antisense (HNF1A-AS1) direction. HNF1A-AS1 is expressed in numerous types of cancers.
Sepehri, Zahra
core
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
MedComm, Volume 7, Issue 4, April 2026.Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
, 2022 Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704) +13 more
core +1 more source
NMHC Ⅱ A在前列腺癌转移中的作用及lncRNA调控轴筛选
Zhongguo shiyan zhenduanxue, 2023 目的 研究NMHCⅡA在前列腺癌转移中的作用并筛选其相关lncRNA调控轴。方法 使用Oncomine数据库分析前列腺癌中NMHCⅡA编码基因MYH9的mRNA表达水平。通过Western bolt检测良性前列腺增生细胞系BPH-1、前列腺癌细胞系PC3及其高转移型亚细胞系PC3M中NMHCⅡA的蛋白表达水平。构建沉默NMHCⅡA的PC3M细胞，筛选稳定感染细胞株，使用Western bolt及细胞免疫荧光染色鉴定沉默效果。CCK-8检测法测定细胞增殖能力 ...
杨玉轩 +5 more
doaj
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
MedComm, Volume 7, Issue 3, March 2026.RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
, 2023 <div>Abstract<p>Long noncoding RNAs (lncRNA) are dysregulated in various human cancers and control tumor development and progression. However, the upstream mechanisms underlying their dysregulation remain unclear. Here, we demonstrate that the expression of hepatocyte nuclear factor 1 homeobox A antisense RNA 1 (HNF1A-AS1) is significantly ...
Peng Gao +4 more
openaire +1 more source