Results 201 to 210 of about 32,692 (251)

Perioperative immunotherapy in resectable HNSCC: biological rationale to practical multidisciplinary implementation. [PDF]

Front Oncol
Bila M, Vander Poorten V, Meulemans J, Huvenne W, De Vos W, Willaert R, De Ceulaer J, Clement PM.   +7 more
europepmc   +1 more source

HNSCC: Tumour Antigens and Their Targeting by Immunotherapy [PDF]

Cells, 2020
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma virus (HPV).
Simon Laban, Adrian Von Witzleben, Chuan Wang   +2 more
exaly   +4 more sources

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Vaccination Expectations in HNSCC

2016
HPV-associated head and neck squamous cell carcinoma (HNSCC), more specifically the incidence of oropharyngeal cancer, is dramatically increasing in industrialized countries. According to what has been learned from anogenital vaccination programs, there are reasons to believe that current human papillomavirus (HPV) vaccinations may be potentially ...
Rautava Jaana, Syrjänen Stina
openaire   +2 more sources

Preclinical models of HPV+ and HPV− HNSCC in mice: An immune clearance of HPV+ HNSCC

Head & Neck, 2009
AbstractBackground.To investigate whether human papilloma virus (HPV)‐specific immune mechanisms can result in tumor clearance, we have created HPV+ and HPV− tonsil cells that form squamous cancers in immune‐competent mice. Here, we determine that an immune‐specific response can clear HPV+ tumor cells and the cellular requirements to mediate this tumor
Robin, Williams, Dong Wook, Lee, Bennett D, Elzey, Mary E, Anderson, Bruce S, Hostager, John H, Lee   +5 more
openaire   +2 more sources

FSCN1 is critical for HNSCC

2023
Abstract Background The study of molecular markers for diagnosis and prognosis is of great clinical significance for HNSCC patients. In this study, we proposed that FSCN1 has a potential indication for prognosis and is essential for the migration of HNSCC.
openaire   +1 more source

Docetaxel induction combination for HNSCC

The Lancet Oncology, 2007
Addition of docetaxel to cisplatin and fl uorouracil in locally advanced unresectable head and neck squamous cell cancer (HNSCC) imp roves progressionfree survival (N Engl J Med 2007; 357: 1695–704) and overall survival (N Engl J Med 2007; 357: 1705–15).
openaire   +2 more sources

Pattern of Failure Among HNSCC

Bengal Journal of Cancer, 2021
Aim: This retrospective study was conducted to evaluate the pattern of recurrence in head and neck squamous cell carcinoma (HNSCC) patients who received a definitive chemo-radiotherapy. Materials and Methods: In this retrospective study, the data of 308 head and neck patients from ...
Afsana Shah, Dinesh Kumar, Govind Preet Singh, Pragya Shukla   +3 more
openaire   +1 more source

Understanding EMT in HNSCC

Otolaryngology–Head and Neck Surgery, 2008
ProblemDown regulation of E‐cadherin is the hallmark of epithelial mesenchymal transition (EMT). The loss of E‐cadherin confers a more invasive phenotype and is one of the steps leading to metastasis. Our recent investigations indicate that inflammatory mediators are potent regulators of EMT in HNSCC.MethodsImmunohistochemical analysis of HNSCC tumor ...
openaire   +1 more source

Preclinical models in HNSCC: A comprehensive review

Oral Oncology, 2017
Head and neck cancer remains a significant public health concern. About 60% of patients die within 5years due to local recurrence. Head and neck squamous cell carcinoma (HNSCC) cell lines are important preclinical models in the search for new therapies against this disease.
Méry, Benoîte, Rancoule, Chloé, Guy, Jean-Baptiste, Espenel, Sophie, Wozny, Anne-Sophie, Battiston-Montagne, Priscillia, Ardail, Dominique, Beuve, Michael, Alphonse, Gersende, Rodriguez-Lafrasse, Claire, Magné, Nicolas   +10 more
openaire   +3 more sources