Results 281 to 290 of about 22,040,645 (295)

Heme Oxygenase-1 (HO-1)

2002
Transplantation is considered one of the most effective ways to overcome terminal dysfunction and failure of some organs. By transplanting organs or tissues between two genetically distinct individuals, an immune mediated response is triggered in the transplant recipient that evokes a potent inflammatory reaction, causing cell injury/death and leading ...
P. O. Berberat, L. Günther, S. Brouard, M. P. Soares, F. H. Bach   +4 more
openaire   +1 more source

Mycoplasmas and Novel HO-1 Inducers: Recent Advances

Current Pharmaceutical Design, 2018
Inflammation and the ways for its regulation: The development of an effective system for the treatment of inflammatory diseases requires comprehensive studies of the cellular signaling molecular networks comprising responses to various stressors, including pathogenic and non-pathogenic microorganisms.
V M, Chernov, O A, Chernova, A A, Mouzykantov, L V, Lopukhov, M V, Trushin   +4 more
openaire   +2 more sources

HO-1 Promotes Unhealthy Obesity

Science Signaling, 2014
Heme oxygenase-1 promotes inflammation and insulin resistance in obesity.
openaire   +1 more source

No Nitric Oxide for HO-1 from Sodium Nitroprusside

Molecular Pharmacology, 2006
Nitric oxide (NO) and NO donors were among the first reported inducers of the tissue-protective protein heme oxygenase-1 (HO-1) with a potential for eventual use in humans. Besides other clinically established NO releasing drugs, sodium nitroprusside (SNP) has frequently been employed as an experimental tool to explore effects of NO on HO-1 and other ...
openaire   +2 more sources

P8 deficiency increases cellular ROS and induces HO-1

Archives of Biochemistry and Biophysics, 2015
The gene p8 encodes for a small cytoprotective protein with no apparent enzymatic activity being proposed to act as co-transcription factor whose expression is increased during inflammation. Recent data from astrocytes demonstrates that p8 suppression leads to induction of heme oxygenase 1 (HO-1). Here, we assessed the cross-talk between p8 and HO-1 in
Sebastian Weis, Tobias Bielow, Ines Sommerer, Juan Iovanna, Cédric Malicet, Joachim Mössner, Albrecht Hoffmeister   +6 more
openaire   +2 more sources

HO-1/HSP32 and Cardiac Stress Signaling

2019
In recent years, increased attention has been gained in elucidating the therapeutic potential of heme oxygenase-1 (HO-1), a rate limiting enzyme involved in the heme metabolism and their pathophysiology of various cardiovascular diseases and heart failure models.
Lakshmikanthan Panneerselvam, Azhwar Raghunath, Kiruthika Sundarraj, Ekambaram Perumal   +3 more
openaire   +1 more source

Induction of HO-1 by NO and inhibition of iNOS expression by HO-1

Annual Meeting of the Japanese Society of Toxicology, 2007
Ashino, Takashi, Yamanaka, Rieko, Shioda, Seiji, Shimokawa, Hiroaki, Sekikawa, Kenji, Iwakura, Yoichiro, Numazawa, Satoshi, Yoshida, Takemi   +7 more
openaire   +1 more source

HO-1

2011
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HO-1

2008
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Oxidative Stress and NRF2/HO-1 Pathway

AbstractFreeradicals that react with biomolecules are reactive molecules that form variouscompounds. Free radicals, divided into ROS and RNS, have negative effects onproteins, carbohydrates, lipids, nucleic acids and DNA. The situation caused bythe imbalance between ROS and antioxidant defenses is called oxidative stress. This affects the regulation of
Çelebi, Fikret, Bolat, Merve, Atasever, Aslıhan   +2 more
openaire   +1 more source