Results 371 to 380 of about 25,300,433 (384)

HO-1/HSP32 and Cardiac Stress Signaling

2019
In recent years, increased attention has been gained in elucidating the therapeutic potential of heme oxygenase-1 (HO-1), a rate limiting enzyme involved in the heme metabolism and their pathophysiology of various cardiovascular diseases and heart failure models.
Lakshmikanthan Panneerselvam, Azhwar Raghunath, Kiruthika Sundarraj, Ekambaram Perumal   +3 more
openaire   +1 more source

Astaxanthin prevents nephrotoxicity through Nrf2/HO-1 pathway

Canadian Journal of Physiology and Pharmacology
Renal toxicity is one of the side effects of methotrexate (MTX). Therefore, this study explored the use of astaxanthin (AST), as a natural carotenoid, against MTX-induced nephrotoxicity emphasizing the changes in oxidative stress and the expression of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 ( Nrf2/HO-1).
Faezeh Lorestani, Ahmad Movahedian, Adel Mohammadalipour, Mohammad Hashemnia, Mohammad Hossein Aarabi   +4 more
openaire   +2 more sources

No Nitric Oxide for HO-1 from Sodium Nitroprusside

Molecular Pharmacology, 2006
Nitric oxide (NO) and NO donors were among the first reported inducers of the tissue-protective protein heme oxygenase-1 (HO-1) with a potential for eventual use in humans. Besides other clinically established NO releasing drugs, sodium nitroprusside (SNP) has frequently been employed as an experimental tool to explore effects of NO on HO-1 and other ...
openaire   +2 more sources

HO-1-induced autophagy establishes a HO-1-p62-Nrf2 positive feedback loop to reduce gut permeability in cholestatic liver disease

Scandinavian Journal of Gastroenterology
The gut-liver axis disruption is a unified pathogenetic principle of cholestatic liver disease (CSLD). Increased gut permeability is the leading cause of gut-liver axis disruption. HO-1 is capable of protecting against gut-liver axis injury. However, it has rarely been reported whether autophagy is involved in HO-1 protecting gut-liver barrier ...
Pingping, Ren, Wei, Lei, Changcheng, Zhao, Zhijun, Duan   +3 more
openaire   +2 more sources

Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats

Environmental science and pollution research international, 2019
A. Mahmoud, Omnia E. Hussein, Walaa G. Hozayen, M. Bin-Jumah, S. M. Abd El-Twab   +4 more
semanticscholar   +1 more source

Oxidative Stress and NRF2/HO-1 Pathway

AbstractFreeradicals that react with biomolecules are reactive molecules that form variouscompounds. Free radicals, divided into ROS and RNS, have negative effects onproteins, carbohydrates, lipids, nucleic acids and DNA. The situation caused bythe imbalance between ROS and antioxidant defenses is called oxidative stress. This affects the regulation of
Çelebi, Fikret, Bolat, Merve, Atasever, Aslıhan   +2 more
openaire   +1 more source

HO-1

2011
openaire   +1 more source

HO-1

2008
openaire   +1 more source

Ho :::;1, :::;c} 0c1. 001

2000
openaire   +1 more source

Human HO-1 Deficiency and Cardiovascular Dysfunction

2001
A Yachie, A Kawashima, K Ohta, Y Saikawa, S Koizumi   +4 more
openaire   +2 more sources