Results 121 to 130 of about 6,534 (190)

Distribution and composition of the lysis cassette of Lactococcus lactis phages and functional analysis of bacteriophage ul36 holin [PDF]

, 2017
The bacteriophage lysis cassette, which comprises a lysin and a holin gene, was analyzed in 18 Lactococcus lactis phages. A muramidase motif was found in the lysins of c2-like phages, while an amidase motif was observed in the lysins of 936-like phages ...
Vukov, Nataša, Moineau, Sylvain, Labrie, Steve, Loessner, Martin J.   +3 more
core  

Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against Klebsiella pneumoniae Infection

Vaccines
Background/Objectives Bacterial ghosts (BGs), non-living empty envelopes of bacteria, are produced either through genetic engineering or chemical treatment of bacteria, retaining the shape of their parent cells.
Svetlana V. Dentovskaya, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Alena S. Kartseva, Tatiana A. Ivashchenko, Vladimir N. Gerasimov, Mikhail E. Platonov, Victoria V. Firstova, Andrey P. Anisimov   +8 more
doaj   +1 more source

A Clostridioides difficile endolysin modulates toxin secretion without cell lysis

Communications Biology
The Clostridia produce and secrete Large Clostridial Glucosylating Toxins (LCGTs) responsible for disease symptoms, but the secretion mechanism is largely unknown. Recently, a holin-like protein was shown to be essential for toxin secretion.
Milena M. Awad, Chathura D. Suraweera, Callum J. Vidor, Auberon Y. Ye-Lin, Galain C. Williams, Steven J. Mileto, Christopher K. Barlow, Sheena McGowan, Dena Lyras   +8 more
doaj   +1 more source

Funktionelle Analyse heterologer Holin Proteinen in lDSthf genetischem Hintergrund

, 2005
Holins are small hydrophobic proteins causing non-specific membrane lesions at the end of bacteriophage multiplication, to promote access of the murein hydrolase to their substrate.
Vukov, Natascha
core  

Evaluation of the Therapeutic Effect of a Bovine-Derived <i>Klebsiella pneumoniae</i> Phage Endolysin on Mouse Mastitis Models. [PDF]

Microorganisms
Yan Z, Wu Z, Zhang J, Zeng Y, Ma C, Wang Y, Yang Z, Huang Y, Luo Z, Yong K, Cao S, Yao X.   +11 more
europepmc   +1 more source

Genetic analysis of F1 cluster phages that infect Mycobacterium smegmatis identifies two distinct holin-like proteins that regulate the host lysis event. [PDF]

PLoS One
Pollenz RS, Ruiz-Houston K, Dean W, Nguyen L.   +3 more
europepmc   +1 more source

Overcoming prokaryotic toxicity: a SUMO-fused secretory platform in Komagataella phaffii for high-yield production of phage holin Hol41. [PDF]

Microb Cell Fact
Huo Z, Wang F, He Y, Chang Z, Feng S, Kang J, Zhong C, Zhang Y, Shi Y.   +8 more
europepmc   +1 more source

Dataset on the genome sequence and biological characteristics of bacteriophage vB_RsoP_PBa1 infecting <i>Ralstonia pseudosolanacearum</i> GMI1000. [PDF]

Data Brief
Wu Q, Yu X, Liu W, Yang Y, Li Z, Fang Z, Xiang L, Weng Q.   +7 more
europepmc   +1 more source

Characterization of the dual start motif of a class II holin gene

, 2001
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the ...
Barenboim, Maxim
core  

TattleTail: A Rule-Based Tool for Identifying Canonical Pyocin-Encoding Gene Clusters in <i>Pseudomonas aeruginosa</i>. [PDF]

Comput Struct Biotechnol J
Pais RG, Chen W, Leptihn S, Hua X, Loh B.   +4 more
europepmc   +1 more source