Results 111 to 120 of about 2,686 (200)
Characterization of Two Salmonella Myoviruses and a Novel Lysis-Inhibition System
PHAGEBackground: Salmonella infecting phages are one of the attractive alternatives to treat antibiotic-resistant infections. Here, we aimed to isolate Salmonella phages and study their lysis genes. Materials and Methods: The water samples were collected from
Prasanth Manohar +2 more
semanticscholar +1 more source
Journal of General Virology, 2016 Holins are phage-encoded hydrophobic membrane proteins that spontaneously and non-specifically accumulate and form lesions in the cytoplasmic membrane. The ORF72 gene (also designated HolGH15) derived from the genome of the Staphylococcus aureus phage GH15 was predicted to encode a membrane protein.
Jun, Song +10 more
openaire +2 more sources
A holin/peptidoglycan hydrolase-dependent protein secretion system [PDF]
Gram-negative bacteria have evolved numerous pathways to secrete proteins across their complex cell envelopes. Here, we describe a protein secretion system which uses a holin membrane protein in tandem with a cell wall editing enzyme to mediate the ...
Saha CK +4 more
core +2 more sources
Probing the function of the two holin-like proteins of bacteriophage SPP1
Virology, 2017 Double-stranded DNA bacteriophages employ holin and endolysin functions to lyse host bacteria after virus multiplication. Holins oligomerize in the cytoplasmic membrane and trigger to form holes that cause cell death. For most systems these holes are also required for endolysin release to the cell wall, where it cleaves the peptidoglycan network.
Sofia, Fernandes, Carlos, São-José
openaire +2 more sources
Mycobacteriophage-mediated lysis : the role of LysB proteins [PDF]
, 2018 Tese de doutoramento, Farmácia (Microbiologia), Universidade de Lisboa, Faculdade de Farmácia, 2018Most bacteriophages, or simply phages, lyse bacterial hosts by producing at least two proteins, holins and endolysins, which allow the release of the viron
Gigante, Adriano Marcelo Dos Santos
core
Frontiers in Microbiology, 2018 Two lytic bacteriophages, WCHABP1 and WCHABP12, were recovered from hospital sewage and were able to infect 9 and 12 out of 18 carbapenem-resistant Acinetobacter baumannii clinical strains, which belonged to different clones.
Weilong Zhou +7 more
doaj +1 more source
Comparative genomic analyses of transport proteins encoded within the genomes of Leptospira species [PDF]
, 2015 Select species of the bacterial genus Leptospira are causative agents of leptospirosis, an emerging global zoonosis affecting nearly one million people worldwide annually.
Saier, Milton H, Buyuktimkin, Bora
core +1 more source
, 2016 Holins are pore-forming membrane proteins synthesized by lytic phages. The second transmembrane domain (TM2) of Mycobacteriophage D29 holin presents an Ala- and Gly-rich sequence, with a currently unknown structure and function. In this study, we present
Lella, Muralikrishna +1 more
core +1 more source
investigating the role in endolysin function
, 2022 Tese de mestrado, Ciências Biofarmacêuticas, 2022, Universidade de Lisboa, Faculdade de Farmácia.Os bacteriófagos (ou simplesmente fagos) são vírus que infetam bactérias.
Temporão, Sofia Isabel Lobato
core +1 more source
Applied MicrobiologyAntimicrobial resistance is a critical global health threat, as conventional antibiotics are increasingly ineffective against multidrug-resistant (MDR) pathogens, particularly ESKAPE organisms. In response, bacteriophages and their derived lytic proteins,
Moses Mwangi +6 more
doaj +1 more source