Results 91 to 100 of about 2,686 (200)
MicrobiologyOpen, Volume 15, Issue 2, April 2026.The recombinant endolysin El1 derived from Enterobacteria bacteriophages showed potent bactericidal activity against Gram‐negative bacteria when applied exogenously, even in the absence of membrane‐permeabilizing agents, such as ethylenediaminetetraacetic acid (EDTA).
Tatjana Kazaka +6 more
wiley +1 more source
The Serratia marcescens NucE protein functions as a holin in Escherichia coli [PDF]
Journal of Bacteriology, 1997 The recently discovered nucC locus of Serratia marcescens encodes the cryptic prophage genes nucE, nucD, and nucC. NucC is required for expression of the S. marcescens nuclease and functions as a transcriptional activator of the nuclease gene, nucA. NucE and NucD are dispensable for nuclease expression but were proposed to allow for secretion of the ...
M, Berkmen, M J, Benedik, U, Bläsi
openaire +2 more sources
Defense Systems and Prophage Detection in Streptococcus mutans Strains
Molecular Oral Microbiology, Volume 41, Issue 2, Page 57-68, April 2026.ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse +3 more
wiley +1 more source
Distribution and composition of the lysis cassette of Lactococcus lactis phages and functional analysis of bacteriophage ul36 holin [PDF]
, 2017 The bacteriophage lysis cassette, which comprises a lysin and a holin gene, was analyzed in 18 Lactococcus lactis phages. A muramidase motif was found in the lysins of c2-like phages, while an amidase motif was observed in the lysins of 936-like phages ...
Vukov, Nataša +3 more
core
Functional Evaluation of a Conserved HNH Endonuclease Gene in Lactococcal Skunavirus Genomes
Microbial Biotechnology, Volume 19, Issue 3, March 2026.The HNH endonuclease HrdP is a highly conserved and essential determinant of infectivity among Skunavirus phages, specifically required for the successful completion of DNA packaging. This key role highlights HrdP as a promising and specific anti‐phage target to protect dairy starter cultures from failure.
Jun‐Hyeok Yu +7 more
wiley +1 more source
Identifying Active Phage Lysins through Functional Viral Metagenomics
, 2010 Recent metagenomic sequencing studies of uncultured viral populations have provided novel insights into the ecology of environmental bacteriophage. At the same time, viral metagenomes could also represent a potential source of recombinant proteins with ...
Jonathan E. Schmitz +2 more
core +1 more source
Advanced Science, Volume 13, Issue 12, 27 February 2026.To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo +3 more
wiley +1 more source
Characterization of the Bacteriophage Lambda Holin and Its Membrane Lesion [PDF]
, 2010 Bacteriophage holins are a diverse group of proteins that are responsible for the spontaneous and specifically-timed triggering of host cell lysis. The best-studied holin, S105 of phage lambda, is known to form lesions, or “holes”, in the inner membrane ...
Dewey, Jill Sayes
core +1 more source
Expanding Horizons in Phage Therapy: Addressing Antibiotic Resistance in Aquaculture
Aquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.ABSTRACT Aquaculture has emerged as a cornerstone of global food security, yet its rapid intensification has precipitated widespread bacterial disease outbreaks and escalating antimicrobial resistance (AMR). This review critically examines the limitations of conventional antibiotic use in aquaculture, highlighting regulatory inconsistencies ...
Anisah Azhar +3 more
wiley +1 more source
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.Analysis of plasmid transconjugants relative to plasmid‐free and plasmid‐carrying Serratia spp. demonstrates erratic disease phenotypes and reduced fitness. Transconjugants also show reduced ability to degrade substrates associated with virulence, supported by transcriptomic data.
Amy L. Vaughan +3 more
wiley +1 more source