Results 91 to 100 of about 1,234 (191)

Maternal Vitamin B12 in Pregnancy and Placental Development

Journal of Nutrition and Metabolism
Vitamin B12, or cobalamin, is an essential nutrient required for diverse physiological functions secondary to its role as a critical cofactor for two mammalian enzymes, methionine synthase and methylmalonyl-CoA mutase. While essential throughout all life
Amrita Arcot, Rachel E. Walker, Kelly Gallagher, Kevin C. Klatt, Alison D. Gernand   +4 more
doaj   +1 more source

Biochemical use of neurofilament light polypeptide and vitamin B12 in relation to diabetic polyneuropathy in Danish adolescents with type 1 diabetes: a cross-sectional study

BMJ Open
Introduction The aim of this study was to investigate serum Neurofilament Light polypeptide (NfL) as a biomarker for diabetic polyneuropathy (DPN) in adolescents with type 1 diabetes (T1D).
Jens Randel Nyengaard, Hatice Tankisi, Vinni Faber Rasmussen, Mathilde Thrysøe, Esben Thyssen Vestergaard, Kurt Kristensen, Tina Parkner, Astrid Juhl Terkelsen   +7 more
doaj   +1 more source

Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly

Frontiers in Physiology, 2019
The intake of adequate amounts and types of nutrients is key for sustaining health and a good quality of life, particularly in the elderly population.
Tobias Konz, Aurelia Santoro, Aurelia Santoro, Laurence Goulet, Alberto Bazzocchi, Giuseppe Battista, Claudio Nicoletti, Claudio Nicoletti, Fawzi Kadi, Rita Ostan, Rita Ostan, Michael Goy, Caroline Monnard, François-Pierre Martin, Jerome N. Feige, Claudio Franceschi, Claudio Franceschi, Serge Rezzi   +17 more
doaj   +1 more source

Unveiling Nutritional Disparities in Infantile Tremor Syndrome: A Focus on Holo-Transcobalamin and Essential Fatty Acids

Journal of Tropical Medicine
Infantile tremor syndrome (ITS), a self-limiting disorder prevalent in the Indian subcontinent, is characterized by tremors, anemia, pigmentary skin changes, developmental delay or regression, and hypotonia.
Rajesh Gupta, Puneet Agrawal, Jyoti Gupta, Jyoti Singh, Ashish Pathak   +4 more
doaj   +1 more source

Diagnostic Accuracy of Holotranscobalamin, Methylmalonic Acid, Serum Cobalamin, and Other Indicators of Tissue Vitamin B12 Status in the Elderly

, 2011
BACKGROUND Vitamin B12 deficiency is common among the elderly, and early detection is clinically important. However, clinical signs and symptoms have limited diagnostic accuracy and there is no accepted reference test
Edward Valente, Conal Cunningham, John M Scott, Anne M Molloy, Per-Magne Ueland, Miriam Casey   +5 more
core   +1 more source

The role of active vitamin B12 (holotranscobalamin) in the development of anemia of pregnancy

Journal of obstetrics and women's diseases, 2015
Modern data on the role of vitamin B12, and its biologically active form holotranscobalamin in particular, in the development of anemia of pregnancy are presented. Information on the vitamin B12 metabolism and its coupling with the folic acid and homocysteine metabolism is supplied. The new automated immunochemiluminescent method for the active vitamin
Gleb Olegovich Kerkeshko, Vladimir Vladimirovich Dorofeykov, Nataliya Aleksandrovna Patrukhina, Elena Vital’evna Mozgovaya   +3 more
openaire   +2 more sources

Diagnosis and treatment of vitamin B12 deficiency--an update

Haematologica, 2006
We represent an update on diagnosing and treatment of vitamin B12 deficiency. Vitamin B12 deficiency should be suspected in all patients with unexplained anaemia and/or neurological symptoms,as well as in patients at risk of developing vitamin B12 ...
AM Hvas, E Nexo
doaj  

Early biomarker response and patient preferences to oral and intramuscular vitamin B12 substitution in primary care: a randomised parallel-group trial

Swiss Medical Weekly, 2017
BACKGROUND Vitamin B12 (VB12) deficiency can be treated with oral high-dose substitution or intramuscular (IM) injection of VB12. Whenever alternative routes of administration exist, patient preferences should be considered when choosing the ...
Corina Metaxas, Deborah Mathis, Cyrill Jeger, Kurt E. Hersberger, Isabelle Arnet, Philipp Walter   +5 more
doaj   +1 more source

Vitamin B12 and Holotranscobalamin Levels in Diabetic Peripheral Neuropathy Patients

Indian journal of Medical Biochemistry, 2016
ABSTRACT Diabetic neuropathy is the most common and debilitating microvascular complication leading to nontraumatic amputations. Identifying the role of vitamin B12 in the etiology of neuropathy is crucial because simple vitamin B12 replacement may reverse neurologic symptoms if confirmed.
Mohammed Noorjahan, Kandregula Madhavi, Chandran Priscilla, Shaik A Jabeen   +3 more
openaire   +1 more source

Cobalamin-binding proteins in normal and cobalamin-deficient older subjects.

, 2003
Item does not contain fulltextBACKGROUND: The causes of cobalamin (vitamin B(12)) deficiency in older people are only partly understood. We investigated the role of the cobalamin-binding proteins and tested the hypothesis that low saturated ...
Hoefnagels, W.H.L., Asselt, D.Z.B. van, Blom, H.J., Segers, M.F.G., Thomas, C.M.G., Wevers, R.A.   +5 more
core   +1 more source