Results 91 to 100 of about 494 (158)

Influence of duration and dose of metformin on cobalamin deficiency in type 2 diabetes patients using metformin

, 2015
Metformin use is associated with cobalamin (vitamin B12) deficiency. However, the influence of both duration and dose of metformin is unclear. Studies using holotranscobalamin, a marker for cellular cobalamin deficiency, are scarce.
Hart, Huberta E., Kooijman-Buiting, Antoinette M J, Kuijs, Ron, Beulens, Joline W J, Rutten, Guy E H M, JC onderzoeksprogramma Cardiovascular Health, Cardiovasculaire Epi Team 1, HAG Diabetes, Circulatory Health   +8 more
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Maternal Vitamin B12 in Pregnancy and Placental Development

Journal of Nutrition and Metabolism
Vitamin B12, or cobalamin, is an essential nutrient required for diverse physiological functions secondary to its role as a critical cofactor for two mammalian enzymes, methionine synthase and methylmalonyl-CoA mutase. While essential throughout all life
Amrita Arcot, Rachel E. Walker, Kelly Gallagher, Kevin C. Klatt, Alison D. Gernand   +4 more
doaj   +1 more source

Biochemical use of neurofilament light polypeptide and vitamin B12 in relation to diabetic polyneuropathy in Danish adolescents with type 1 diabetes: a cross-sectional study

BMJ Open
Introduction The aim of this study was to investigate serum Neurofilament Light polypeptide (NfL) as a biomarker for diabetic polyneuropathy (DPN) in adolescents with type 1 diabetes (T1D).
Jens Randel Nyengaard, Hatice Tankisi, Vinni Faber Rasmussen, Mathilde Thrysøe, Esben Thyssen Vestergaard, Kurt Kristensen, Tina Parkner, Astrid Juhl Terkelsen   +7 more
doaj   +1 more source

Screening for metabolic vitamin B-12 deficiency by holotranscobalamin in patients suspected of vitamin B-12 deficiency:a multicentre study [PDF]

, 2012
Background: Vitamin B-12 deficiency occurs frequently, especially among the elderly. However, screening for vitamin B-12 deficiency is hampered by poor sensitivity of the existing total vitamin B-12 assay.
van Wijnen, Merel, Heiner-Fokkema, Rebecca M R, Muller Kobold, Anna; id_orcid, Pekelharing, J Maurits M, Sanders, Edward, Rammeloo, Ton, Trienekens, Paul H, Lindemans, Jan, Heil, Sandra G, Muller Kobold, Anna, de Jonge, Robert, Adriaansen, Henk J, de Rotte, Maurits C F J, Heiner-Fokkema, Rebecca M R; id_orcid, Heiner-Fokkema, RMR, Pekelharing, JMM, Jonge, R, Heil, Sandra, Rotte, Maurits, Kobold, ACM, Rammeloo, T, Trienekens, PH, Adriaansen, HJ, Lindeman, J, Wijnen, M   +24 more
core   +1 more source

Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly

Frontiers in Physiology, 2019
The intake of adequate amounts and types of nutrients is key for sustaining health and a good quality of life, particularly in the elderly population.
Tobias Konz, Aurelia Santoro, Aurelia Santoro, Laurence Goulet, Alberto Bazzocchi, Giuseppe Battista, Claudio Nicoletti, Claudio Nicoletti, Fawzi Kadi, Rita Ostan, Rita Ostan, Michael Goy, Caroline Monnard, François-Pierre Martin, Jerome N. Feige, Claudio Franceschi, Claudio Franceschi, Serge Rezzi   +17 more
doaj   +1 more source

Unveiling Nutritional Disparities in Infantile Tremor Syndrome: A Focus on Holo-Transcobalamin and Essential Fatty Acids

Journal of Tropical Medicine
Infantile tremor syndrome (ITS), a self-limiting disorder prevalent in the Indian subcontinent, is characterized by tremors, anemia, pigmentary skin changes, developmental delay or regression, and hypotonia.
Rajesh Gupta, Puneet Agrawal, Jyoti Gupta, Jyoti Singh, Ashish Pathak   +4 more
doaj   +1 more source

The role of active vitamin B12 (holotranscobalamin) in the development of anemia of pregnancy

Journal of obstetrics and women's diseases, 2015
Modern data on the role of vitamin B12, and its biologically active form holotranscobalamin in particular, in the development of anemia of pregnancy are presented. Information on the vitamin B12 metabolism and its coupling with the folic acid and homocysteine metabolism is supplied. The new automated immunochemiluminescent method for the active vitamin
Gleb Olegovich Kerkeshko, Vladimir Vladimirovich Dorofeykov, Nataliya Aleksandrovna Patrukhina, Elena Vital’evna Mozgovaya   +3 more
openaire   +2 more sources

Association of cognitive impairment with combinations of vitamin B₁₂-related parameters.

, 2011
BACKGROUND: Low vitamin B₁₂ concentrations have been associated with higher risks of cognitive impairment, but whether these associations are causal is uncertain.
Harold Hin, Robert Clarke, Dorte L Lildballe, Ebba Nexo, Paul Sherliker, Sergey Fedosov   +5 more
core   +1 more source

Vitamin B12 and Holotranscobalamin Levels in Diabetic Peripheral Neuropathy Patients

Indian journal of Medical Biochemistry, 2016
ABSTRACT Diabetic neuropathy is the most common and debilitating microvascular complication leading to nontraumatic amputations. Identifying the role of vitamin B12 in the etiology of neuropathy is crucial because simple vitamin B12 replacement may reverse neurologic symptoms if confirmed.
Mohammed Noorjahan, Kandregula Madhavi, Chandran Priscilla, Shaik A Jabeen   +3 more
openaire   +1 more source

Diagnosis and treatment of vitamin B12 deficiency--an update

Haematologica, 2006
We represent an update on diagnosing and treatment of vitamin B12 deficiency. Vitamin B12 deficiency should be suspected in all patients with unexplained anaemia and/or neurological symptoms,as well as in patients at risk of developing vitamin B12 ...
AM Hvas, E Nexo
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