Results 31 to 40 of about 1,234 (191)

Holotranscobalamin levels in mid vitamin B12 values [PDF]

open access: yes, 2016
Amaç: B12 vitamini, vücutta önemli fonksiyonlar üstlenmektedir. Eksikliğinde pek çok hematolojik ve nörolojik bozukluklar ile kendini gösterebilmektedir. Erken dönemde tedaviye başlanmadığında ise bu nörolojik bozukluklar kalıcı olabilmektedir.
Yaprak, Ebru   +5 more
core   +1 more source

Cobalamin and holotranscobalamin measurements in the obese

open access: yes, 2022
Pretilost se smatra jednom od najčešćih bolesti modernog društva s kompleksnom etiologijom koja se razvija zbog neuravnoteženog unosa i potrošnje energije pri čemu je dominacija na strani unosa.
Oreški, Elena
core   +1 more source

Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum

open access: yesHaematologica, 2007
We confirm a decrease in cobalamins during pregnancy, and report that the active part of cobalamins (holotranscobalamin, holoTC) remains unchanged. The decrease in cobalamins is explained by a decreased holohaptocorrin (holoHC), suggesting that holoTC ...
Anne L. Morkbak*   +3 more
doaj   +1 more source

Genetic polymorphisms of vitamin B12 and folate transporter proteins and depression in postpartum period: A case-control study

open access: yesJournal of Affective Disorders Reports, 2021
Vitamin B12 and folate deficiency have been linked to the susceptibility of developing depression in the postpartum period. Transcobalamin-2 (TCN-2) and reduced folate carrier (RFC-1) are essential for the cellular uptake of vitamin B12 and folate ...
Pooja Dhiman   +6 more
doaj   +1 more source

Coexistence of pernicious anemia and prostate cancer - 'an experiment of nature' involving vitamin B12 modulation of prostate cancer growth and metabolism: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction This report presents the clinical and laboratory course of a patient with prostate cancer and severe vitamin B12 deficiency undergoing watchful waiting for prostate cancer.
Rainville Christa   +2 more
doaj   +1 more source

Relationship between the Levels of Holotranscobalamin and Vitamin B12

open access: yesAnnals of Laboratory Medicine, 2010
To date, the determination of serum vitamin B12 levels has been the most common laboratory test for the assessment of vitamin B12 status; however, the diagnostic accuracy of this test is low. To obtain a more sensitive marker, a new test to measure holotranscobalamin (holoTC) levels has been introduced. In this study, we assessed 45 patients for whom a
Kwang Sook, Woo   +4 more
openaire   +2 more sources

Diagnostic reliability of serum active B12 (holo-transcobalamin) in true evaluation of vitamin B12 deficiency: Relevance in current perspective

open access: yesBMC Research Notes, 2022
Objective Measurement of total vitamin B12 (vit B12) concentration raised concerns over early detection of vit B12 deficiency due to its clinical unreliability.
Rinini Dastidar, Kunal Sikder
doaj   +1 more source

Pre-conceptional Maternal Vitamin B12 Supplementation Improves Offspring Neurodevelopment at 2 Years of Age: PRIYA Trial

open access: yesFrontiers in Pediatrics, 2021
Background: The first thousand days window does not include the pre-conceptional period. Maternal pre-conceptional health has a profound influence on early embryonic development (implantation, gastrulation, placentation etc).
Naomi D'souza   +13 more
doaj   +1 more source

Measurement of holotranscobalamin in assessing vitamin B12 status [PDF]

open access: yes, 2016
Cilj istraživanja bio je ispitati je li holotranskobalamin osjetljiviji pokazatelj deficita vitamina B12 u odnosu na kobalamin, te postoji li povezanost između kobalamina i holotranskobalamina s homocisteinom.
Vuk, Darko
core   +1 more source

The role of holotranscobalamin in examination of vitamin B12 status

open access: yesMedicinski pregled, 2008
Introduction. Holotranscobalamin contains biologically available cobalamin because only holotranscobalamin promotes the uptake of the cobalamin therein by all cells, via specific receptors. Therefore holotranscobalamin has been proposed as a potentially useful alternative indicator of vitamin B12 status.
Velibor, Cabarkapa   +4 more
openaire   +3 more sources

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