Results 21 to 30 of about 494 (158)

Diagnostic Accuracy of Holotranscobalamin, Vitamin B12, Methylmalonic Acid, and Homocysteine in Detecting B12 Deficiency in a Large, Mixed Patient Population. [PDF]

, 2020
Four biomarkers are commonly employed to diagnose B12 deficiency: vitamin B12 (B12), holotranscobalamin (HoloTC), methylmalonic acid (MMA), and homocysteine (Hcy).
Risch, Martin, Renz, Harald, Risch, Lorenz, Stanga, Zeno, Nydegger, Urs, Vazquez Van Dyck, Maclovia, Wiesner, Jacobo, Jarquin Campos, Araceli, Risch M, Risch L, Wiesner J, Jarquin Campos A, Nydegger U, Vazquez Van Dyck M, Renz H, Stanga Z   +15 more
core   +3 more sources

Relationship Between the Levels of Holotranscobalamin and Vitamin B12 in Children [PDF]

Indian Journal of Hematology and Blood Transfusion, 2017
The purpose of this study was to evaluate the relationship between the plasma holoTC and serum vitamin B12 in children and to identify a cutoff cobalamin values according to holoTC. One hundred and fifty-five children were enrolled into the study. All children were evaluated for hemoglobin, vitamin B12, folate, ferritin and holoTC levels. Children were
Yarali, Nese, ÖZKAN, SEÇİL, Kizilgün, Murat, Ok Bozkaya, Ikbal, Tunc, Bahattin   +4 more
openaire   +4 more sources

Association of maternal folate and B12 vitamin status with gestational diabetes mellitus: Still an open issue

, 2023
Objectives: There is conflicting evidence about the role of folate and B12 in gestational diabetes mellitus (GDM) onset. The association of vitamin status with GDM was therefore revalued, also measuring the B12 active form holotranscobalamin. Methods:
Dominika Szoke, Leila Rovegno, S. Borille, M. Panteghini, M. Chibireva, Mauro Panteghini, D. Szoke, L. Rovegno, Mariia Chibireva, Simona Borille   +9 more
core   +1 more source

Holotranscobalamin Concentrations Across Human Pregnancy: A Systematic Review

Current Developments in Nutrition
Leigh A Martin, Payton Forsyth, Rita Castro, Omar Lweno, Emily R Smith, Alison D Gernand   +5 more
doaj   +2 more sources

Cobalamin and holotranscobalamin measurements in the obese

, 2022
Pretilost se smatra jednom od najčešćih bolesti modernog društva s kompleksnom etiologijom koja se razvija zbog neuravnoteženog unosa i potrošnje energije pri čemu je dominacija na strani unosa.
Oreški, Elena
core   +1 more source

Relationship between the Levels of Holotranscobalamin and Vitamin B12

Annals of Laboratory Medicine, 2010
To date, the determination of serum vitamin B12 levels has been the most common laboratory test for the assessment of vitamin B12 status; however, the diagnostic accuracy of this test is low. To obtain a more sensitive marker, a new test to measure holotranscobalamin (holoTC) levels has been introduced. In this study, we assessed 45 patients for whom a
Kwang Sook, Woo, Kyung Eun, Kim, Joon Seok, Park, Joo In, Park, Jin Yeong, Han   +4 more
openaire   +2 more sources

Genetic polymorphisms of vitamin B12 and folate transporter proteins and depression in postpartum period: A case-control study

Journal of Affective Disorders Reports, 2021
Vitamin B12 and folate deficiency have been linked to the susceptibility of developing depression in the postpartum period. Transcobalamin-2 (TCN-2) and reduced folate carrier (RFC-1) are essential for the cellular uptake of vitamin B12 and folate ...
Pooja Dhiman, Raji Ramachandran Pillai, Anand Babu Wilson, Nancy Premkumar, Balaji Bharadwaj, P. Veena, Soundravally Rajendiran   +6 more
doaj   +1 more source

Coexistence of pernicious anemia and prostate cancer - 'an experiment of nature' involving vitamin B₁₂ modulation of prostate cancer growth and metabolism: a case report

Journal of Medical Case Reports, 2009
Introduction This report presents the clinical and laboratory course of a patient with prostate cancer and severe vitamin B12 deficiency undergoing watchful waiting for prostate cancer.
Rainville Christa, Kutik Seth, Tisman Glenn   +2 more
doaj   +1 more source

Holotranscobalamin levels in mid vitamin B12 values [PDF]

, 2016
Amaç: B12 vitamini, vücutta önemli fonksiyonlar üstlenmektedir. Eksikliğinde pek çok hematolojik ve nörolojik bozukluklar ile kendini gösterebilmektedir. Erken dönemde tedaviye başlanmadığında ise bu nörolojik bozukluklar kalıcı olabilmektedir.
Yaprak, Ebru, Cüre, Medine Cumhur, Topaloğlu, Hacer Bilgin, Baykan, Özgür, Kırbaş, Aynur, Arpa, Medeni   +5 more
core   +1 more source

Diagnostic reliability of serum active B12 (holo-transcobalamin) in true evaluation of vitamin B12 deficiency: Relevance in current perspective

BMC Research Notes, 2022
Objective Measurement of total vitamin B12 (vit B12) concentration raised concerns over early detection of vit B12 deficiency due to its clinical unreliability.
Rinini Dastidar, Kunal Sikder
doaj   +1 more source