Objective: To systematically review the evidence for whether habitual or different levels of experimental intake of vitamin B12 from diet and supplements is sufficient to ensure adequate B12 status in groups most susceptible to vitamin B12 deficiency ...
Linnea Bärebring +8 more
doaj +1 more source
Oral administration of cyanocobalamin for functional vitamin В12 deficiency: efficacy and safety
The prevalence of vitamin В12 deficiency is about 3—16% in the general population, while in older people, it ranges from 10 to 20%. An increase in the proportion of people on reduced-calorie diets, the widespread use of drugs that can result in vitamin ...
E. V. Shikh +2 more
doaj +1 more source
Clinical follow-up of children with high vitamin B12 values: should we worry?
Background. Requests of Vitamin B12 test increased with the widespread use of autoanalysers. Although the cause of requests was deficiency suspicions, an important ratio of high levels of Vitamin B12 were reported to physicians by laboratory ...
Davut Albayrak, Canan Albayrak
doaj +1 more source
Diagnostic Accuracy of Holotranscobalamin, Vitamin B12, Methylmalonic Acid, and Homocysteine in Detecting B12 Deficiency in a Large, Mixed Patient Population. [PDF]
Four biomarkers are commonly employed to diagnose B12 deficiency: vitamin B12 (B12), holotranscobalamin (HoloTC), methylmalonic acid (MMA), and homocysteine (Hcy).
Risch, Martin +7 more
core +3 more sources
Holotranscobalamin as an Indicator of Dietary Vitamin B12 Deficiency [PDF]
We report that serum holotranscobalamin (holoTC) compares favorably with serum vitamin B12 for identifying vegans likely to have vitamin B12 deficiency as judged by measurements of the metabolites methylmalonic acid (MMA) and homocysteine (tHcy). We also report that measurement of holoTC may possibly replace combined testing with serum vitamin B12 (B12)
Lloyd-Wright, Z +4 more
openaire +5 more sources
Neurological disorders in vitamin B12 deficiency [PDF]
The review discusses thesteps of vitamin B12 metabolism and its role in maintaining of neurological functions. The term "vitamin B12 (cobalamin)" refers to several substances (cobalamins) of a very similar structure. Cobalamin enters the body with animal
Ch S Pavlov +3 more
doaj +1 more source
Diagnostic Associations of Hypercobalaminemia in Indian Population [PDF]
Introduction: Serum cobalamin (Cbl) measurements are routinely done to rule out its deficiency. Surprisingly, a high fraction of these patients display hypercobalaminemia.
Swarnima Singh, Rekha Kumar
doaj +1 more source
Holotranscobalamin Concentrations Across Human Pregnancy: A Systematic Review
Leigh A Martin +5 more
doaj +2 more sources
Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. [PDF]
The importance of maternal dietary choline for fetal neural development and later cognitive function has been well-documented in experimental studies.
Brian T F Wu +4 more
doaj +1 more source
Algorithm for the early diagnosis of vitamin B12 deficiency in elderly people
Background: The elderly population is particularly at risk for developing vitamin B12-deficiency. Serum cobalamin does not necessarily reflect a normal B12 status. The determination of methylmalonic acid is not available in all laboratories.
Gonzalo Palacios +5 more
doaj +1 more source

