Results 61 to 70 of about 1,234 (191)

Vitamin B12 and Reproductive Health: Clinical Insights, Emerging Mechanistic Understanding, and Nutritional Aspects

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Epidemiological data from assisted reproductive technologies (ART) link vitamin B12 (VitB12) deficiency to shorter gestation, low birth weight, and reduced live birth rates. VitB12 also plays a critical role in fertility for both sexes by supporting gamete quality.
Aimee Rachel Mathew, Erisa Selita, Chiara Regano, Claudia Bianco, Veronica Corsetti, Virve Cavallucci, Sandra Moreno, Ada Maria Tata, Marco Fidaleo   +8 more
wiley   +1 more source

Controversies in NEN: An ENETS position statement on nutritional support in neuroendocrine neoplasms

Journal of Neuroendocrinology, Volume 37, Issue 12, December 2025.
Abstract Neuroendocrine neoplasms (NEN) themselves and also their treatment may cause malnutrition, inducing changes in physiological behaviour and eventually leading to increased rates of morbidity and mortality. Malnutrition is a common, under‐recognised and under‐treated condition in patients with NEN, and there are limited data available on the ...
Simona Grozinsky‐Glasberg, Johannes Hofland, Stephanie Alband, Yasmin Chotai de Lima, Adina Croitoru, Wanda Geilvoet, Peter Igaz, Beata Kos‐Kudła, Guenter J. Krejs, Alessandro Laviano, Francesco Panzuto, Anguraj Sadanandam, Ana Paula Santos, Staffan Welin, Rajaventhan Srirajaskanthan, V. Ambrosini, D. K. Bartsch, E. Baudin, N. Begum, E. Christ, J. Cros, T. Denecke, C. M. Deroose, C. Dromain, M. Falconi, N. Fazio, L. Fernandez‐Cuesta, R. Garcia‐Carbonero, A. Grossman, G. Kaltsas, A. Kasajima, A. Kjaer, G. Klöppel, U. P. Knigge, A. Lamarca, S. W. Langer, T. V. Luong, W. Martin, M. McNamara, D. O'Toole, S. Partelli, M. Pavel, A. Perren, R. Salazar, J. Schrader, H. Sorbye, A. Sowa‐Staszczak, E.‐J. Speel, P. Stalberg, M. Tesselaar, E. Tiensuu Janson, M. Tsoli, M. Volante, T. Walter   +53 more
wiley   +1 more source

Active B12: A Rapid, Automated Assay for Holotranscobalamin on the Abbott AxSYM Analyzer [PDF]

Clinical Chemistry, 2008
AbstractBackground: Conventional tests for vitamin B12 deficiency measure total serum vitamin B12, whereas only that portion of vitamin B12 carried by transcobalamin (holotranscobalamin) is metabolically active. Measurement of holotranscobalamin (holoTC) may be more diagnostically accurate for detecting B12 deficiency that requires therapy.
Jeff, Brady, Lesley, Wilson, Lynda, McGregor, Edward, Valente, Lars, Orning   +4 more
openaire   +2 more sources

Multicentre evaluation of the Roche Elecsys® Active B12 (holotranscobalamin) electro-chemiluminescence immunoassay [PDF]

, 2019
Background: Vitamin B12 deficiency is a common disorder. In circulation, vitamin B12 is bound to transcobalamin (holotranscobalamin), which is considered the active form of cobalamin. The objective of this study was to evaluate the analytical performance
Sun, Y. (Yuli), Heil, S.G. (Sandra), Rijke, Y.B. (Yolanda) de, Findeisen, P. (Peter), Luebcke, S. (Silke), Bodenburg, P. (Petra)   +5 more
core   +1 more source

Vegan diet and nutritional status in infants, children and adolescents: A position paper based on a systematic search by the ESPGHAN Nutrition Committee

Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 5, Page 1318-1345, November 2025.
Abstract Vegan and other plant‐based diets are becoming increasingly popular in the paediatric age group. There is limited evidence in the current medical literature to determine whether a vegan diet is adequate for children, since the currently available society position papers are based on narrative reviews and expert opinion.
Elvira Verduci, Jutta Kӧglmeier, Nadja Haiden, Laura Kivelä, Barbara de Koning, Susan Hill, Veronica Luque, Sissel J. Moltu, Lorenzo Norsa, Miguel Saenz De Pipaon, Francesco Savino, Jiri Bronsky   +11 more
wiley   +1 more source

Adherence to Indonesia's Dietary Guidelines Among Lactating Women: Insights for Policy and Practice

Maternal &Child Nutrition, Volume 21, Issue 4, October 2025.
Most lactating women in Indonesia consume excessive starchy staples and insufficient vegetables, fruits, and water, while protein‐rich food intake is closer to recommendations. Overall dietary adherence improves nutrient adequacy but does not consistently translate into better nutritional biomarkers or growth outcomes, highlighting the need to refine ...
Sofa Rahmannia, Kevin Murray, Gina Arena, Aly Diana, Rosalind Gibson, Siobhan Hickling   +5 more
wiley   +1 more source

Concomitant use of metformin and proton pump inhibitors increases vitamin B12 deficiency risk in type 2 diabetes

Journal of Diabetes Investigation, Volume 16, Issue 6, Page 1020-1027, June 2025.
The concomitant use of metformin and PPI was significantly associated with an increased risk of vitamin B12 deficiency in patients with type 2 diabetes. ABSTRACT Introduction Vitamin B12 deficiency is one of the adverse drug reactions of metformin and proton pump inhibitors (PPIs).
Choungwon Jung, Soyoung Park, Hyunah Kim
wiley   +1 more source

Determination of serum holotranscobalamin concentrations with the AxSYM active B-12 assay: cut-off point evaluation in the clinical laboratory [PDF]

, 2009
Background: A reliable early marker is required for diagnosis of cobalamin deficiency. We calculated an appropriate holotranscobalamin (HoloTC) cut-off point for identifying cobalamin deficiency using an immunoenzymatic assay.
Galli C., Lonati, Silvia, Bamonti, Fabrizia, R. De Giuseppe, Moscato G. A., C. Novembrino, Lonati S., DE GIUSEPPE R, GALLI C, NOVI C, Novembrino C., Uva V., F. Bamonti, Galli, Claudio, R. Maiavacca, Novembrino, Cristina, MOSCATO GA, MAIAVACCA R., NOVEMBRINO C, Bamonti F., V. Uva, C. Novi, Gregori D., UVA V, LONATI S, C. Galli, Giuseppe, Rachele De, Novi, Claudia, Novi C., De Giuseppe R., G. A. Moscato, GREGORI, DARIO, D. Gregori, Moscato, Giovanna Antonella, Maiavacca, Rita, BAMONTI F, Uva, Valentina, S. Lonati   +37 more
core   +1 more source

Multiomics profiling and parenteral nutrition weaning in pediatric patients with intestinal failure: A longitudinal cohort study

Journal of Parenteral and Enteral Nutrition, Volume 49, Issue 4, Page 451-459, May 2025.
Abstract Background Intestinal failure (IF) is a life‐limiting condition that includes a variety of intestinal pathologies. Currently, there are few clinical biomarkers that reflect intestinal function or a patient's potential to wean off parenteral nutrition (PN), making it difficult to predict the clinical trajectory.
Niklas Tappauf, Yvonne Lamers, Ho Pan Sham, Hannah G. Piper   +3 more
wiley   +1 more source

The Effect of a Lecture‐Based Educational Intervention to Improve the Nutrition Knowledge and Behavior of Plant‐Based Seventh‐Day Adventists Living in the United Kingdom

Health Science Reports, Volume 8, Issue 2, February 2025.
ABSTRACT Background and Aims The Adventist lifestyle, which encourages the consumption of a vegetarian or vegan diet, has been associated with several health benefits; however, the nutrition knowledge of Adventists about essential nutrients in the context of plant‐based diets has not yet been assessed, therefore, this study evaluated the efficacy of an
Robert K. Janko, Irmgard Haussmann, Ashok Patel   +2 more
wiley   +1 more source