Results 91 to 100 of about 119,960 (296)

Combination antiretroviral therapy -associated lipodystrophy : insights into pathogenesis and treatment [PDF]

, 2011
Introduction: Combination antiretroviral therapy (cART) has decreased morbidity and mortality of individuals infected with human immunodeficiency virus type 1 (HIV-1). Its use, however, is associated with adverse effects which increase the patients risk
Sevastianova, Ksenia
core  

Lhx6 regulates the migration of cortical interneurons from the ventral telencephalon but does not specify their GABA phenotype [PDF]

, 2004
The LIM homeodomain family of transcription factors is involved in many processes in the developing CNS, ranging from cell fate specification to connectivity.
Alifragis, P, Liapi, A, Parnavelas, JG
core   +1 more source

Transcriptomic validation of a 7,12 Dimethylbenz(a)anthracene (DMBA)‐induced leukemia rat model: Parallels with human leukemogenesis

Animal Models and Experimental Medicine, EarlyView.
7,12‐Dimethylbenz[a]anthracene (DMBA) could induce leukemia and other types of cancers in rat models. Transcriptomics revealed gene expression profile that parallels with human leukemia. DMBA‐induced differential gene expression could validate the developed rat model.
Khaldoon Alsamman, Omar S. El‐Masry
wiley   +1 more source

Predictability of hand skill and cognitive abilities from craniofacial width in right- and left-handed men and women: relation of skeletal structure to cerebral function [PDF]

, 2002
Recently, a family of homeobox genes involved in brain and craniofacial development was identified. In light of this genetic background, we hypothesized that some functional characteristics of human brain (hand skill, cognition) may be linked to some ...
Dayi, Ertunc, Okuyan, Mukadder, Tan, Uner   +2 more
core   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Timing the generation of distinct retinal cells by homeobox proteins.

PLoS Biology, 2006
The reason why different types of vertebrate nerve cells are generated in a particular sequence is still poorly understood. In the vertebrate retina, homeobox genes play a crucial role in establishing different cell identities.
Sarah Decembrini, Massimiliano Andreazzoli, Robert Vignali, Giuseppina Barsacchi, Federico Cremisi   +4 more
doaj   +1 more source

Protein evolution of ANTP and PRD homeobox genes

BMC Evolutionary Biology, 2008
Background Although homeobox genes have been the subject of many studies, little is known about the main amino acid changes that occurred early in the evolution of genes belonging to different classes.
Holland Peter WH, Vieira Cristina P, Fonseca Nuno A, Vieira Jorge   +3 more
doaj   +1 more source

Acromial Osteotomy for Dynamic Posterior Shoulder Instability

Arthroscopy Techniques, EarlyView.
Abstract Posterior shoulder instability is less prevalent than anterior instability but shows a rising incidence, particularly among young and active individuals. Diagnosis is often challenging due to nonspecific symptoms, leading to delays and underestimation of prevalence. Its etiology is multifactorial, including traumatic events, iatrogenic causes,
Ricardo Mendes, José Carlos Garcia Jr, Matheus Barcelos, Airthon Correia, Lucas Fiori, Mauricio Raffaelli, Marcelo Mello   +6 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Evaluating the Level of Homeobox B8 and its Association with Cell Lung Cancer Proliferation Downregulation: A Systematic Review and Meta-analysis [PDF]

International Journal of Scientific Research in Dental and Medical Sciences
Background and aim: Homeobox family genes have been identified as cancer growth regulators. There is no meta-analysis or comprehensive study on the activity of Homeobox B8 (HOXB8) in lung cancer.
Maryam Hassanpour Amnieh, Samira Jalalinezhad, Mahsa Hajizadeh, Majid Hajizadeh   +3 more
doaj   +1 more source