Results 71 to 80 of about 55,050 (178)

Transcriptional precision in photoreceptor development and diseases – Lessons from 25 years of CRX research

Frontiers in Cellular Neuroscience
The vertebrate retina is made up of six specialized neuronal cell types and one glia that are generated from a common retinal progenitor. The development of these distinct cell types is programmed by transcription factors that regulate the expression of ...
Yiqiao Zheng, Yiqiao Zheng, Shiming Chen, Shiming Chen, Shiming Chen   +4 more
doaj   +1 more source

Integrated Multi‐Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep

Integrative Zoology, EarlyView.
SNaPshot‐validated GWAS results demonstrated significant correlations between candidate single nucleotide polymorphisms (SNPs) and body size traits in Tibetan sheep. Concurrently, hematoxylin and eosin staining, alongside muscle fiber analysis, confirmed pronounced morphological differences in muscle tissue between sheep of varying conformation.
Dehui Liu, Xue Li, Fei Tian, Xuexia Li, Wenxia Li, Buying Han, Ming Jiang, Yanlan Liu, Xiliu Hu, Xue Xiang, Wulong Ma, Guangcai Bao, Rong Li, Guoxiang Bao, Sijia Liu, Kai Zhao, Dehong Tian   +16 more
wiley   +1 more source

Pbx homeodomain proteins pattern both the zebrafish retina and tectum

, 2007
Background Pbx genes encode TALE class homeodomain transcription factors that pattern the developing neural tube, pancreas, and blood. Within the hindbrain, Pbx cooperates with Hox proteins to regulate rhombomere segment identity.
Callander, D., Berry, K.M., Wuennenberg-Stapleton, K., Moens, C.B., Koss, R., Ngai, J., Waskiewicz, A.J., Hagey, D.W., Erickson, T., French, C.R., Stout, J.   +10 more
core   +1 more source

Characterization of Homeodomain Proteins at the Aβ Sublocus in Schizophyllum commune and Their Role in Sexual Compatibility and Development

Journal of Fungi
The A mating-type locus in Schizophyllum commune, which encodes homeodomain (HD) transcription factors, is essential for regulating sexual compatibility and development.
Chen Chu, Dongxu Li, Changhong Liu
doaj   +1 more source

microRNA‐mediated control of cell fate specification and patterning in Marchantia polymorpha

New Phytologist, EarlyView.
The gemma developmental program in Marchantia polymorpha is coordinated by MpMIR166‐mediated repression of MpC3HDZ and auxin homeostasis. Summary MicroRNAs (miRNAs) are small non‐coding RNA molecules essential for growth and development in eukaryotes. In plants, the master gene DICER‐LIKE 1 (DCL1) catalyzes the biogenesis of miRNAs by processing double‐
Adolfo Aguilar‐Cruz, Eduardo Flores‐Sandoval, Ye Xu, Yu Yu, Ximena Gutiérrez‐Ramos, Cristian Y. González‐Rangel, Omar Oltehua‐López, Ana E. Dorantes‐Acosta, Joshua T. Trujillo, Hirotaka Kato, Kimitsune Ishizaki, Rebecca A. Mosher, Liam Dolan, Xuemei Chen, Daniel Grimanelli, Jim Haseloff, John L. Bowman, Mario A. Arteaga‐Vazquez   +17 more
wiley   +1 more source

A Gain‐of‐Function Mutation in DELLA Selectively Alters Protein Interactions to Regulate Wheat Tiller Angle and Plant Height

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant architecture, especially plant height and tiller angle, plays a pivotal role in determining wheat yield. In this study, we characterize a wheat mutant termed prostrate and semidwarf 1 (prose1), exhibiting both a prostrate growth habit and semidwarfism.
Chaoqun Dong, Dejie Du, Yingying Li, Siyao Jia, Zhe Zhang, Yiqing Wang, Shuai Zheng, Xincheng Wang, Mingming Xin, Yingyin Yao, Lingling Chai, Zhongfu Ni, Qixin Sun, Jie Liu   +13 more
wiley   +1 more source

RAP2.3 Is Required for MYB51 and SIGMA3 Expression During the Response of Arabidopsis thaliana to Multifactorial Stress Combination

Plant, Cell &Environment, EarlyView.
ABSTRACT In nature, plants are subjected to multiple environmental stress factors simultaneously or sequentially. Recent studies revealed that when three or more stress factors impact a plant simultaneously (termed ‘multifactorial stress combination’; MFSC), plant survival declines, even if the intensity of each individual stress involved in the MFSC ...
Ranjita Sinha, María Ángeles Peláez‐Vico, Devasantosh Mohanty, Lidia S. Pascual, Sara I. Zandalinas, Zhen Lyu, Ahmad Bereimipour, Rajeev K. Azad, Trupti Joshi, Ron Mittler   +9 more
wiley   +1 more source

Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis.

Frontiers in Pharmacology, 2014
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, as well as for their maintenance in the adult. Homeobox genes comprise an important family of transcription factors, which are characterised by a well ...
Padma eMurthi, Padma eMurthi, Mohamed eAbumaree, Mohamed eAbumaree, Bill eKalionis, Bill eKalionis   +5 more
doaj   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Cytosolic sequestration of Prep1 influences early stages of T cell development.

PLoS ONE, 2008
ObjectivePrep1 and Pbx2 are the main homeodomain DNA-binding proteins of the TALE (three amino acid loop extension) family expressed in the thymus. We previously reported reduced Pbx2 expression and defective thymocyte maturation in Prep1 hypomorphic ...
Dmitry Penkov, Martina Palazzolo, Anna Mondino, Francesco Blasi   +3 more
doaj   +1 more source