Results 31 to 40 of about 72,239 (257)

Implantable, Label‐Free NIR‐Based Porous Silicon Biosensor for Monitoring Biomarkers in Interstitial Fluid

Advanced Sensor Research, EarlyView.
Implantable biosensors hold the promise to revolutionize the way disease diagnosis and progression during treatment are viewed. However, in the current state of art, their efficiency is limited by certain material challenges. Porous Silicon (pSi) is a viable material for in vivo monitoring of biomarkers, and its potential as an implantable biosensor is
Pritam Sharma, Jann Harberts, Raquel Sánchez‐Salcedo, Pouya Dehghankelishadi, Nicolas Hans Voelcker   +4 more
wiley   +1 more source

Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress

Antioxidants, 2023
Homocysteine is an amino acid containing a free sulfhydryl group, making it probably contribute to the antioxidative capacity in the body. We recently found that plasma total homocysteine (total-Hcy) concentration increased with time when whole blood ...
Mingxin Ye, Hui Li, Hongjun Luo, Yongyin Zhou, Wenhong Luo, Zhexuan Lin   +5 more
doaj   +1 more source

Gamma‐Glutamyl Cysteine Ligase Activity as a Proxy for Human T Cell Function and Drug‐Induced Immunosuppression

Advanced Science, EarlyView.
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González, Carmen Salto‐Giron, Mehek Ningoo, Laura Espinar‐Barranco, Rafael Salto, Jose Manuel Paredes, Rosario Herranz, Angel Orte, Miguel Fribourg, Juan A. González‐Vera   +9 more
wiley   +1 more source

Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study

BMC Cardiovascular Disorders, 2018
Background Homocysteine has been long considered a risk factor for atherosclerosis. However, cardiovascular events cannot be reduced through homocysteine lowering by B vitamin supplements.
Ching-Yu Julius Chen, Tzu-Ching Yang, Christopher Chang, Shao-Chun Lu, Po-Yuan Chang   +4 more
doaj   +1 more source

The Association between Homocysteine, Arterial Stiffness and Executive Function Middle-age and Older Women

Artery Research, 2020
Age-related decreases in executive function and an increase in arterial stiffness and plasma homocysteine levels are related to the risk of dementia. However, the association between executive function, arterial stiffness, and homocysteine levels remains
Ai Shindo-Hamasaki, Nobuhiko Akazawa, Reiko Momma, Seiji Maeda   +3 more
doaj   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Homocysteine and Diabetic Retinopathy [PDF]

Diabetes Care, 2008
OBJECTIVE—Homocysteine is an emerging risk factor for cardiovascular and nondiabetic ocular vaso-occlusive diseases. However, studies of the relationship between homocysteine and diabetic retinopathy have reported inconsistent results. The purpose of this study was to evaluate the relationship between plasma total homocysteine concentration and ...
Brazionis, L., Rowley Sr., K., Itsiopoulos, C., Harper, C. A., O'dea, K.   +4 more
openaire   +4 more sources

Transfer Learning Empowered Multiple‐Indicator Optimization Design for Terahertz Quasi‐Bound State in the Continuum Biosensors

Advanced Science, EarlyView.
This study proposes a pioneering method leveraging transfer learning to optimize multiple indicators in meta‐biosensor design, achieving the multiple‐indicator comprehensive optimization. By adopting frequency shift as a unified criterion, this study quantifies the contribution ratio of each performance indicator to the biosensor, which facilitates ...
Shengfeng Wang, Bingwei Liu, Xu Wu, Zuanming Jin, Yiming Zhu, Linjie Zhang, Yan Peng   +6 more
wiley   +1 more source

Does Omega-3 Fatty Acid Supplementation Have Beneficial Effects on Plasma Homocysteine, Insulin Resistance and Lipid Profile of Type 2 Diabetic Patients? A Randomized Clinical Trial

Journal of Nutrition and Food Security, 2018
Background: This study was conducted to determine the effects of n-3 PUFAs supplementation on plasma homocysteine (Hcy) level, lipid profile and insulin resistance in patients with type 2 diabetes (T2D).
Faezeh Poursoleiman, Hassan Mozaffari-Khosravi, Akram Naghdipour Biregani   +2 more
doaj  

The role of homocysteine in endothelial dysfunction [PDF]

The Moldovan Medical Journal, 2017
Background: Homocysteine is a sulfur-containing intermediate product in the normal metabolism of methionine, an essential amino acid. Hyperhomocysteinemia defines the state in which concentrations of homocysteine exceeds normal level.
Elena Visternicean
doaj   +1 more source