Results 51 to 60 of about 143,735 (277)

Increased Plasma Homocysteine Levels Are Associated with Left Ventricular Hypertrophy in Hypertensive Patients with Normal Renal Function

open access: yesKidney & Blood Pressure Research, 2023
Introduction: Renal function has an important bearing on plasma homocysteine levels. Plasma homocysteine is related to left ventricular hypertrophy (LVH).
Lingyu Zhang   +5 more
doaj   +1 more source

Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis [PDF]

open access: yes, 2018
Background. The lead (Pb) exposure crisis in Flint, Michigan has passed from well-publicized event to a footnote, while its biological and social impact will linger for lifetimes.
Bayon, Baindu L.   +3 more
core   +2 more sources

The homocysteine controversy [PDF]

open access: yesJournal of Inherited Metabolic Disease, 2010
AbstractMild to moderate hyperhomocysteinemia has been identified as a strong predictor of cardiovascular disease, independent from classical atherothrombotic risk factors. In the last decade, a number of large intervention trials using B vitamins have been performed and have shown no benefit of homocysteine‐lowering therapy in high‐risk patients.
Smulders, Y.M., Blom, H.J.
openaire   +4 more sources

A hidden cause of infertility in hypothyroid patients [PDF]

open access: yes, 2020
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy   +4 more
core   +1 more source

The Association between Homocysteine, Arterial Stiffness and Executive Function Middle-age and Older Women

open access: yesArtery Research, 2020
Age-related decreases in executive function and an increase in arterial stiffness and plasma homocysteine levels are related to the risk of dementia. However, the association between executive function, arterial stiffness, and homocysteine levels remains
Ai Shindo-Hamasaki   +3 more
doaj   +1 more source

Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress

open access: yesAntioxidants, 2023
Homocysteine is an amino acid containing a free sulfhydryl group, making it probably contribute to the antioxidative capacity in the body. We recently found that plasma total homocysteine (total-Hcy) concentration increased with time when whole blood ...
Mingxin Ye   +5 more
doaj   +1 more source

Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein

open access: yesJournal of Lipid Research, 1998
Elevated plasma homocysteine (homocysteinemia) are presumed to be responsible for the development of coronary artery disease, however, the precise etiology is unclear.
Eric Ferguson   +3 more
doaj   +1 more source

Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis. [PDF]

open access: yes, 2019
The risk of adverse effects of nitrous oxide (N2O) exposure is insufficiently recognized despite its widespread use. These effects are mainly reported through case reports. We conducted an individual patient data meta-analysis to assess the prevalence of
Filhine-Tresarrieu, Pierre   +10 more
core   +3 more sources

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study

open access: yesBMC Cardiovascular Disorders, 2018
Background Homocysteine has been long considered a risk factor for atherosclerosis. However, cardiovascular events cannot be reduced through homocysteine lowering by B vitamin supplements.
Ching-Yu Julius Chen   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy