Results 61 to 70 of about 72,239 (257)
ABSTRACT Background Psoriasis is a chronic immune‐mediated inflammatory disease with a global prevalence of 2%–3% and 1.3% in Brazil. It is associated with comorbidities such as obesity, hypertension, and diabetes, all of which contribute to increased cardiovascular risk due to systemic inflammation and endothelial dysfunction.
Tiago A. S. Costa+2 more
wiley +1 more source
Elevated plasma homocysteine (homocysteinemia) are presumed to be responsible for the development of coronary artery disease, however, the precise etiology is unclear.
Eric Ferguson+3 more
doaj
Faulty homocysteine recycling in diabetic retinopathy
Background Although hyperglycemia is the main instigator in the development of diabetic retinopathy, elevated circulating levels of a non-protein amino acid, homocysteine, are also associated with an increased risk of retinopathy.
Renu A. Kowluru+2 more
doaj +1 more source
Thiol‐X Chemistry: A Skeleton Key Unlocking Advanced Polymers in Additive Manufacturing
Additive manufacturing and thiol‐X chemistry form a powerful combination for fabricating a diverse array of advanced polymers to address contemporary engineering applications. Thiol‐X reactions offer versatile polymerization mechanisms, “click” reactivity, functional group tolerance, desirable properties, and compatibility over a broad range of 3D ...
James Anthony Dicks, Chris Woolard
wiley +1 more source
Neurotoxic and neuroprotective effects of homocysteine and hydrogen sulfide
Homocysteine is a sulfhydryl-containing amino acid derived from methionine. The cellular concentration of homocysteine is regulated by two key pathways: remethylation back to methionine or transsulfuration to cysteine with simultaneous production of ...
G.F. Sitdikova+2 more
doaj
Homocysteine is an indirect metabolite of methionine metabolism, as well as of creatinine, and it plays an important role in many biochemical processes.
Eugenia Murawska-Ciałowicz
doaj
Homocysteine and Beh??et Disease
Three of the five patients with seriously complicated Behçet disease had uveitis and two had high homocysteine levels. Gastrointestinal and central nervous system involvement were the other two serious complications. The highest level of plasma homocysteine level (50 mmol/L) in this study belonged to a patient with Behçet disease, Budd-Chiari Syndrome,
Nalbant, Selim+6 more
openaire +4 more sources
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar+4 more
wiley +1 more source
Thetin–homocysteine transmethylase. Some further characteristics of the enzyme from rat liver [PDF]
George Maw
openalex +1 more source
Over half of patients with colorectal cancer experience severe chemotherapy‐induced side effects. The B‐vitamin folate may play a role in these side effects, potentially by altering DNA methylation, a mechanism of gene regulation. Our comprehensive literature search identified studies investigating DNA methylation associated with folate status/intake ...
Nienke R. K. Zwart+3 more
wiley +1 more source