Results 61 to 70 of about 72,239 (257)

The Impact of Methotrexate on Cardiovascular Outcomes in Psoriasis: A Systematic Review and Meta‐Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic immune‐mediated inflammatory disease with a global prevalence of 2%–3% and 1.3% in Brazil. It is associated with comorbidities such as obesity, hypertension, and diabetes, all of which contribute to increased cardiovascular risk due to systemic inflammation and endothelial dysfunction.
Tiago A. S. Costa   +2 more
wiley   +1 more source

Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein

open access: yesJournal of Lipid Research, 1998
Elevated plasma homocysteine (homocysteinemia) are presumed to be responsible for the development of coronary artery disease, however, the precise etiology is unclear.
Eric Ferguson   +3 more
doaj  

Faulty homocysteine recycling in diabetic retinopathy

open access: yesEye and Vision, 2020
Background Although hyperglycemia is the main instigator in the development of diabetic retinopathy, elevated circulating levels of a non-protein amino acid, homocysteine, are also associated with an increased risk of retinopathy.
Renu A. Kowluru   +2 more
doaj   +1 more source

Thiol‐X Chemistry: A Skeleton Key Unlocking Advanced Polymers in Additive Manufacturing

open access: yesMacromolecular Materials and Engineering, EarlyView.
Additive manufacturing and thiol‐X chemistry form a powerful combination for fabricating a diverse array of advanced polymers to address contemporary engineering applications. Thiol‐X reactions offer versatile polymerization mechanisms, “click” reactivity, functional group tolerance, desirable properties, and compatibility over a broad range of 3D ...
James Anthony Dicks, Chris Woolard
wiley   +1 more source

Neurotoxic and neuroprotective effects of homocysteine and hydrogen sulfide

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2018
Homocysteine is a sulfhydryl-containing amino acid derived from methionine. The cellular concentration of homocysteine is regulated by two key pathways: remethylation back to methionine or transsulfuration to cysteine with simultaneous production of ...
G.F. Sitdikova   +2 more
doaj  

The Impact of Wingate and Progressive Tests on Homocysteine, Vitamin B6, B12 and Folic Acid Levels in Athletes' Blood

open access: yesCentral European Journal of Sport Sciences and Medicine, 2014
Homocysteine is an indirect metabolite of methionine metabolism, as well as of creatinine, and it plays an important role in many biochemical processes.
Eugenia Murawska-Ciałowicz
doaj  

Homocysteine and Beh??et Disease

open access: yesJCR: Journal of Clinical Rheumatology, 2003
Three of the five patients with seriously complicated Behçet disease had uveitis and two had high homocysteine levels. Gastrointestinal and central nervous system involvement were the other two serious complications. The highest level of plasma homocysteine level (50 mmol/L) in this study belonged to a patient with Behçet disease, Budd-Chiari Syndrome,
Nalbant, Selim   +6 more
openaire   +4 more sources

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar   +4 more
wiley   +1 more source

Folate‐Associated DNA Methylation and Chemotherapy‐Induced Toxicities in Patients With Colorectal Cancer

open access: yesMolecular Nutrition &Food Research, EarlyView.
Over half of patients with colorectal cancer experience severe chemotherapy‐induced side effects. The B‐vitamin folate may play a role in these side effects, potentially by altering DNA methylation, a mechanism of gene regulation. Our comprehensive literature search identified studies investigating DNA methylation associated with folate status/intake ...
Nienke R. K. Zwart   +3 more
wiley   +1 more source

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