Results 51 to 60 of about 14,760,741 (339)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Studying Effect of Climatic Variables on Temporal Distribution of Air Pollution Using Sentinel-5P Data in Mazandaran Province, Iran [PDF]
محیط زیست و مهندسی آبStudying air pollution distribution and factors is crucial for control. The research focused on analyzing air pollution distribution and its correlation with climatic variables in Mazandaran Province from 2018 to 2022 using Remote Sensing.
Hadigheh Bahrami-Pichaghchi +2 more
doaj +1 more source
Continuous testing for Poisson process intensities: A new perspective on scanning statistics
, 2017 We propose a novel continuous testing framework to test the intensities of Poisson Processes. This framework allows a rigorous definition of the complete testing procedure, from an infinite number of hypothesis to joint error rates.
Picard, Franck +2 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Preparation of Yangtze River Delta Sediment Reference Materials
Yankuang ceshi, 2017 More than 10 harbour and estuarine sediment reference materials have been developed in the United States, Canada and other countries, but most of them focus on organic pollutants and radionuclide, and lack certified values.
XIN Wen-cai +3 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Journal of Water and Climate ChangeClimate change (CC) significantly influences agricultural water productivity, it is advisable to consider the adapting irrigation regimes to observed changes in precipitation patterns.
Venkatesh Gaddikeri +5 more
doaj +1 more source
Yankuang ceshi, 2015 Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) is currently an important microanalysis technique in the geoscience field. Development of related reference materials is a key for this technique. In this paper, the types, elemental
WU Shi-tou, WANG Ya-ping, XU Chun-xue
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source