Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. [PDF]
Hughes JH +12 more
europepmc +1 more source
The preparation of homogentisic acid and of 2:5-dihydroxyphenylethylamine [PDF]
G, Leaf, A, Neuberger
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Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria. [PDF]
Rutland DA +8 more
europepmc +1 more source
Ochronotic Deposition in Alkaptonuria: Semiquinone-Mediated Oxidative Coupling and Metabolic Drivers of Homogentisic Acid Accumulation. [PDF]
Grasso D +5 more
europepmc +1 more source
A case of alkaptonuria presenting with unexplained dark-stained diapers and spurious hyperoxaluria and proteinuria due to homogentisic acid interference. [PDF]
Vanhove T +6 more
europepmc +1 more source
INHIBITION AND ACTIVATION OF THE OXIDATION OF HOMOGENTISIC ACID
openaire +2 more sources
Analysis of Melanin-like Pigment Synthesized from Homogentisic Acid, with or without Tyrosine, and Its Implications in Alkaptonuria. [PDF]
Taylor AM, Vercruysse KP.
europepmc +1 more source
Two rapid and direct chromatographic methods based on reverse phase-high performance liquid chromatography (RP-HPLC) and ion chromatography (IC) were developed for the determination of homogentisic acid (HA) in honey.
Tapparo, Andrea +6 more
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Who can devise a process to utilize grapes for grape acid? /
Mode of access ...
American Grape Acid Association.
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