A heart so black: a case of alkaptonuric ochronosis of the aortic and mitral valves in a female patient with severe aortic valve stenosis and coronary artery disease. [PDF]
Kamougeros A +5 more
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Qiancao (<i>Rubia</i> spp.) - a comprehensive metabolomics analysis of the five core species. [PDF]
Zhang M +6 more
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Characterisation of the Self-Sufficient Cytochrome P450 CYP116B234 From Rhodococcus globerulus and Its Suggested Native Role in 2-Hydroxyphenylacetic Acid Metabolism. [PDF]
Kundral S +9 more
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Genomic Analysis of Carotenoid and Vitamin E Biosynthetic Pathways in the Extremophilic Red Alga <i>Cyanidioschyzon merolae</i>. [PDF]
Hui Y +10 more
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Functional Characterization of <i>HGD</i> Gene Variants by Minigene Splicing Assay. [PDF]
Nekrasov A +3 more
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Homogentisic Acid Derivatives from Miliusa balansae
Journal of Natural Products, 2003The new homogentisic acid derivatives miliusol (1b) and miliusolide (2) from Miliusa balansae were isolated and structurally determined by spectroscopic means. The relative configurations of the new 1b and its known acetate 1a were established. Furthermore, the symmetric ether bis(2-hydroxyphenyl)methyl ether 3, which was isolated for the first time ...
Do Thu, Huong +2 more
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A Synthesis of Homogentisic Acid
Transactions of the Kansas Academy of Science (1903-), 1973Homogentisic acid (2,5-dihydroxyphenylacetic acid) is the substance found in the urine in alcaptonuria, an inborn error of metabolism involving incomplete oxidation of phenylalanine and tyrosine (1). The urine of individuals afBicted with the disease turns dark owning to oxidation of the acid to substituted quinhydrone complexes.
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Homogentisic acid interference in routine urine creatinine determination
Molecular Genetics and Metabolism, 2010We report the artifactual elevation of homogentisic acid (HGA) in urine from alkaptonuric patients after replacing the creatinine method (Jaffe reaction) in our laboratory with an automated enzymatic method. Samples with elevated HGA by GC-MS had lower creatinine values as determined by the enzymatic method than by the Jaffe reaction.
Perry R, Loken +8 more
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