Asynchronous replication of homologous loci on human active and inactive X chromosomes.
Malgorzata Schmidt, Barbara R. Migeon
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A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli [PDF]
Maria D. Lalioti
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HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis
Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman+3 more
wiley +1 more source
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity. Abstract Purpose To report novel BEST1 variants in six Chinese families with bestrophinopathies of two different inheritance modes and analyze the intrafamilial phenotypic diversity.
Shangying Yang+8 more
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Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2 [PDF]
Amy J. MacQueen, Anne M. Villeneuve
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ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith+9 more
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Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe. [PDF]
Ding DQ+5 more
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Introduction of Single Base Substitutions at Homologous Chromosomal Sequences by Adeno-associated Virus Vectors [PDF]
Naoki Inoue+3 more
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The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou+6 more
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Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
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