Modification of Different Pulps by Homologous Overexpression Alkali-Tolerant Endoglucanase in Bacillus subtilis Y106 [PDF]
Scientific Reports, 2017 Cellulase (mainly endoglucanase, EG) has been used in pulp modification for improving paper quality through environmentally friendly process. But low activity in alkaline pH and high filter paper activity (FPA) were still obstacles for extending the ...
Meimei Wang +4 more
doaj +5 more sources
Scientific ReportsThe overexpression of Polo-like kinase 1 (PLK1) is associated with poor clinical outcomes in various malignancies, making it an attractive target for anticancer therapies. Although recent studies suggest PLK1’s involvement in homologous recombination (HR)
Takeuchi Osamu, Anna S Sedukhina
exaly +8 more sources
Comparative Genomics Analysis Combined with Homologous Overexpression Reveals the Mechanism of Species-Specific Acid Stress Resistance in Bifidobacterium animalis [PDF]
FoodsMost Bifidobacterium species exhibit poor stress tolerance, which greatly limits their stability and industrial application. In contrast, Bifidobacterium animalis shows remarkable tolerance and distinct species-specific characteristics.
Li Lin +9 more
doaj +2 more sources
Amplification and Overexpression of E2 Ubiquitin Conjugase UBE2T Promotes Homologous Recombination in Multiple Myeloma [PDF]
Blood Advances, 2019 Key Points UBE2T is frequently amplified and/or overexpressed and is required for homologous recombination activity in multiple myeloma cells. UBE2T is a potential therapeutic target to increase chemosensitivity in multiple myeloma cells.
Subodh Kumar +2 more
exaly +5 more sources
Advanced Strategies for Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production: PHA Synthase Homologous Overexpression in the Extremophile Haloferax mediterranei [PDF]
Marine DrugsBioplastics such as poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) are promising alternatives to conventional plastics. However, the high production cost limits their industrial application.
Alexandra Simica +4 more
doaj +2 more sources
Impact of homologous overexpression of PR10a gene on improving salt stress tolerance in transgenic Solanum tuberosum [PDF]
Journal of Genetic Engineering and BiotechnologyAbiotic stresses severely affected crop productivity and considered to be a major yield limiting factor for crop plant. The tolerance to these stresses is a very complex phenomenon involving a wide array of molecular, biochemical and physiological ...
Moemen S. Hanafy +3 more
doaj +2 more sources
Immune pathway activation in gastric cancers with LINE-1 retrotransposon overexpression and homologous recombination deficiency [PDF]
Experimental and Molecular MedicineThere are only a few whole genome sequencing studies of human gastric cancer (GC) conducted so far. We performed comprehensive whole genome, bulk RNA, and methylation sequencing analyses of 100 samples of GC and adjacent normal tissue.
Young Jin Kim +25 more
doaj +2 more sources
Frontiers in Cell and Developmental BiologyExonuclease 1 (EXO1) is a critical enzyme in homologous recombination (HR) and is implicated in cancer progression, with overexpression linked to poor prognosis in multiple tumor types.
Koichiro Tsugawa, Anna S Sedukhina
exaly +3 more sources
Frontiers in Plant Science, 2022 Although full sequence data of several embryogenesis-related genes are available in conifers, their functions are still poorly understood. In this study, we focused on the transcription factor WUSCHEL-related HOMEOBOX 2 (WOX2), which is involved in ...
Seyedeh Batool Hassani +4 more
doaj +1 more source
Fermentation, 2023 Thioesterases play an essential role in the metabolism of fatty acids since they are considered one of the key enzymes to change the total amount and composition of fatty acid in an organism’s cells.
Feifei Xin +10 more
doaj +1 more source