Bt agave: why it is time to explore a new biotechnological frontier
Drylands cover 41% of Earth, requiring sustainable crops. Agave, drought‐ and heat‐adapted, offers high‐value products with low water needs. Pests limit yield, yet Bacillus thuringiensis (Bt) Cry proteins, successful in other plants, remain unexploited in Agave.
Aline Vitória Corim Marim +3 more
wiley +1 more source
Prevalence of homologous recombination deficiency in ovarian, primary peritoneal, and/or fallopian tube cancer: results from HALO-Taiwan subset. [PDF]
Liou WS, Chao A, Sheu BC, Yeh LS, Wu CH.
europepmc +1 more source
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji +13 more
wiley +1 more source
Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis, and Treatment. [PDF]
Shah B, Hussain M, Seth A.
europepmc +1 more source
Information Dynamics and Learning in Complex Adaptive Systems: Toward a Transdisciplinary Framework
ABSTRACT This article develops a framework for understanding learning and adaptation in complex adaptive systems. Drawing from neuroscience, systems theory, information theory and quantum field theory, it examines how information processing, plasticity and systemic coherence emerge from distributed, nonlinear and feedback‐driven interactions. It argues
Anderson de Souza Sant'Anna
wiley +1 more source
Long-term outcomes of eribulin‑based neoadjuvant chemotherapy for triple‑negative breast cancer patients stratified by homologous recombination deficiency status: results of the randomized JBCRG-22 study. [PDF]
Masuda N +17 more
europepmc +1 more source
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
CG>TG mutation frequency as negative predictor of homologous recombination deficiency in ovarian and breast cancer. [PDF]
Romanovsky E +8 more
europepmc +1 more source
One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer +4 more
wiley +1 more source

