Results 211 to 220 of about 52,625 (269)

Homologous recombination deficiency in breast cancer: genomic characteristics, clinical implications, and predictive value in neoadjuvant therapy. [PDF]

Front Oncol
Huang J, Luan F, Yan L, Liang X, Ma X, An Y, Hu S, Gao G, Wang Y, Yang J, Dong D.   +10 more
europepmc   +1 more source

Genetic Tools in the Nakaseomyces clade for Evolutionary Comparisons of Signal Transduction Pathways

Yeast, EarlyView.
ABSTRACT The genus Nakaseomyces provides four species that are closely related but have different characteristics. For example, N. glabratus (formerly known as Candida glabrata) is a common human pathogen, whereas N. bracarensis and N. nivariensis have been isolated in clinical settings but are not common human pathogens. N.
Maria Abraham, Christine L. Iosue, Dennis D. Wykoff   +2 more
wiley   +1 more source

Homologous recombination deficiency in newly diagnosed advanced ovarian cancer across nine Middle East countries: prevalence, real-world testing pathways, and treatment implications. [PDF]

BMC Cancer
Shash E, Vardar MA, Taskiran C, Boujassoum S, Riromar J, Aboutaleb A, Sadek F, Samy E, Bahaj W.   +8 more
europepmc   +1 more source

Refining the Vertebrate Mitochondrial 12S rRNA Secondary Structure by Comparative Analysis

Integrative Zoology, EarlyView.
This flowchart outlines the comprehensive workflow of the study, integrating diverse bioinformatics tools (e.g., NCBI2GO, SSU‐align, bpRNA) and their sequential interactions. Key steps, such as data preprocessing, structural prediction, and evolutionary analysis, are depicted with their respective outputs (e.g., standardized records, consensus ...
Fengxia Li, Gengyun Niu, Renzeng Du, Kun Wan, David Roy Smith, Meicai Wei, Haihe Shi   +6 more
wiley   +1 more source

Complex Relationships Between Homologous Recombination Deficiency (HRD) Score and Mutational Status of Homologous Recombination Repair (HRR) Genes in Prostate Carcinomas. [PDF]

Int J Mol Sci
Iyevleva AG, Aleksakhina SN, Sokolenko AP, Otradnova EA, Nikitina AS, Kashko KA, Syomina MV, Shestakova AD, Kuligina ES, Morozova NS, Popov SV, Vyazovcev PV, Luchkova TY, Peremyshlenko AS, Topuzov TM, Gudkova OM, Orlova RV, Levushkin AV, Moiseev DO, Shkodenko ON, Gubarev DV, Dzyuba AV, Povorina IY, Agaeva AV, Kutyan VF, Grigoryan MM, Orlov AN, Lefterov SI, Belousov AV, Nechaeva MN, Vorobyeva EN, Amirkhanova IK, Kryukova NV, Zatulivetrova LI, Gomboeva AB, Krivtsov VN, Shchiglik OI, Prokudina NV, Butunina NA, Belyaev AM, Imyanitov EN.   +40 more
europepmc   +1 more source

Gut Microbiota of Gray Snub‐Nosed Monkeys: Adaptation to Seasonal Variations Through Energy Compensation and Thermogenesis

Integrative Zoology, EarlyView.
Based on metagenome‐assembled genomes (MAGs), the gut microbiota of the gray snub‐nosed monkeys recovered 1229 non‐redundant MAGs. The gut microbiota showed an enhanced capacity to produce energy substrates with increased conversion activity of these substrates during winter.
Yue Sun, Mingyi Zhang, Xiaochen Wang, Xiaolong Huang, Yanze Yu, Huijuan Pan, Haibo Li, Lei Shi, Wei Yang, Chen Zhang, Bo Ding, Xun Liu, Jianfeng Li, Changjiang Qian, Boxing Cheng, Chao Zhang, Jingcheng Ran, Ming Li   +17 more
wiley   +1 more source

Robust Assessment of Homologous Recombination Deficiency Genomic Instability by OncoScan Microarrays. [PDF]

J Mol Diagn
Lara Gutierrez A, Halbwedl I, Sauer S, Regitnig P, Petru E, Seeböck R, Schubert S, Peternell C, Bodó K, Prein K, Kashofer K.   +10 more
europepmc   +1 more source

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

Integrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei, Hua Li, Yeyu Chen, Huanchao Yang, Jun Du, Zhaobin Song   +5 more
wiley   +1 more source

A Novel Droplet Digital PCR Assay for BRCA1 and RAD51C Methylation: Advancing Homologous Recombination Deficiency Detection in Ovarian Cancer. [PDF]

J Mol Diagn
Michel C, Simon A, Witz A, Hanriot I, Dardare J, Betz M, Brun M, Gilson P, Merlin JL, Harlé A.   +9 more
europepmc   +1 more source