Results 141 to 150 of about 1,081,032 (300)

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Genetic, hormonal, and transcriptomic analyses highlight the crucial role of phytohormones in first branch angle regulation in pepper

BMC Plant Biology
Background The first branch angle (FBA) is a critical trait influencing plant architecture, yield, and mechanized harvesting efficiency in pepper (Capsicum annuum L.). However, the genes and regulatory processes involved remain largely unclear.
Xinjie Yuan, Xuejun Chen, Kunhua Zhou, Gang Lei, Yueqin Huang, Gege Li, Yu Fang, Jubin Wang, Rong Fang   +8 more
doaj   +1 more source

IQD1 Involvement in Hormonal Signaling and General Defense Responses Against Botrytis cinerea. [PDF]

Front Plant Sci, 2022
Barda O, Levy M.
europepmc   +1 more source

Signaling Credit Risk in Agriculture: Implications for Capital Structure Analysis [PDF]

Signaling is an important element in the lender-borrower relationship that influences the cost and availability of debt capital to agricultural borrowers.
Barry, Peter J., Katchova, Ani L., Zhao, Jianmei   +2 more
core  

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Evolutionary Assembly and Future Design of Gibberellin Signaling

Advanced Science
Gibberellin (GA) signaling is widely regarded as a canonical hormone‐controlled growth pathway, yet accumulating evidence suggests that it emerged through stepwise evolutionary assembly rather than as a pre‐formed regulatory system.
Weishu Fan, Xihan Chen, Dan Li, Xiuhua Gao, Xiangdong Fu   +4 more
doaj   +1 more source

Wounding rapidly alters transcription factor expression, hormonal signaling, and phenolic compound metabolism in harvested sugarbeet roots. [PDF]

Front Plant Sci, 2022
Fugate KK, Finger FL, Lafta AM, Dogramaci M, Khan MFR.   +4 more
europepmc   +1 more source

The Simple Analytics of Price Signaling Quality [PDF]

We present a diagrammatic and step-by-step analysis of price signaling quality. Because quality is a continuum on the real positive line, out-of-equilibrium beliefs need not be specified, i.e., every positive price is a positive outcome in equilibrium ...
Marc Santugini, Leonard J. Mirman
core  

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Phosphatidic Acid in Plant Hormonal Signaling: From Target Proteins to Membrane Conformations. [PDF]

Int J Mol Sci, 2022
Kolesnikov Y, Kretynin S, Bukhonska Y, Pokotylo I, Ruelland E, Martinec J, Kravets V.   +6 more
europepmc   +1 more source