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Frontiers in EndocrinologySpinal cord injury (SCI), a debilitating neurological disorder with complex pathophysiology, involves primary mechanical trauma followed by multifactorial cascades of secondary inflammation, oxidative stress, and apoptosis.
Wenliang Guo +3 more
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Nuclear jasmonate and salicylate signaling and crosstalk in defense against pathogens
Frontiers in Plant Science, 2013 An extraordinary progress has been made over the last two decades on understanding the components and mechanisms governing plant innate immunity. After detection of a pathogen, effective plant resistance depends on the activation of a complex signaling ...
Roberto eSolano, Selena eGimenez-Ibanez
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Brassinosteroids and Plant Steroid Hormone Signaling [PDF]
The Plant Cell, 2002 Steroids play a role as essential hormones in plants as well as in animals. Plants produce numerous steroids and sterols, some of which are recognized as hormones in animals ([Geuns, 1978][1]; [Jones and Roddick, 1988][2]).
Bishop, G., Koncz, C.
openaire +3 more sources
Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview [PDF]
peer reviewedThe endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman's life based on estrogen and progesterone fluctuations.
Zielonka, Manon +7 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Poultry Science: Maintenance of calcium and phosphorus homeostasis in laying hens is crucial for preservation of skeletal integrity and eggshell quality, though physiological regulation of these systems is incompletely defined.
Micaela Sinclair-Black +6 more
doaj +1 more source
How Microbes Twist Jasmonate Signaling around Their Little Fingers
Plants, 2016 Plant immunity relies on a complex network of hormone signaling pathways in which jasmonic acid (JA) plays a central role. Successful microbial pathogens or symbionts have developed strategies to manipulate plant hormone signaling pathways to cause ...
Selena Gimenez-Ibanez +2 more
doaj +1 more source
Nitrate and hormonal signaling crosstalk for plant growth and development
, 2019 Nitrate is an essential macronutrient for plants, a primary nitrogen source in natural and human-made ecosystems. Nitrate can also act as a signaling molecule that directs genome-wide gene expression changes with an impact on plant metabolism, physiology,
O’Brien, José Antonio +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Poultry ScienceIntestinal supply of calcium and phosphorus is crucial for the maintenance of eggshell quality and skeletal integrity in laying hens; however, the hormones and transporters that govern mineral uptake and homeostasis within the small intestine and ceca ...
Micaela Sinclair-Black +6 more
doaj +1 more source