Results 81 to 90 of about 1,081,032 (300)

Environmental and hormonal signaling pathways targeting or mediated by plant aquaporins

, 2016
Environmental and hormonal signaling pathways targeting or mediated by plant aquaporins. 27.
Shahzad, Zaigham, Grondin, Alexandre, Maurel, Christophe, Prado, Karine, Rodrigues, Olivier, Santoni, Veronique, Tournaire-Roux, Colette, Verdoucq, Lionel   +7 more
core   +2 more sources

Electrical Signaling, Photosynthesis and Systemic Acquired Acclimation

Frontiers in Physiology, 2017
Electrical signaling in higher plants is required for the appropriate intracellular and intercellular communication, stress responses, growth and development. In this review, we have focus on recent findings regarding the electrical signaling, as a major
Magdalena Szechyńska-Hebda, Magdalena Szechyńska-Hebda, Maria Lewandowska, Stanisław Karpiński   +3 more
doaj   +1 more source

Insufficient androgen and FSH signaling may be responsible for the azoospermia of the infantile primate testes despite exposure to an adult-like hormonal milieu

, 2012
Background: In humans, as well as in other higher primates, the infantile testis is exposed to an adult-like hormonal milieu, but spermatogenesis is not initiated at this stage of primate development. In the present study, we examined the molecular basis
Majumdar, Subeer S., Sarda, Kanchan, Bhattacharya, Indrashis, Plant, Tony M.   +3 more
core   +1 more source

Augmenting endogenous wnt signaling improves skin wound healing [PDF]

, 2013
Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R., Fang Mark Y., Girija R Dhamdhere, Anthony E. Oro, Bo Liu, Fang, Mark Y, Whyte, Jemima L., Helms Jill A., Wilfred R. Manzano, Nick D. Evans (474290), Manzano, Wilfred R, Howard Y. Chang (215450), Smith, Andrew A, Manzano, Wilfred R., Whyte, Jemima L, Jemima L. Whyte (474287), Nick D Evans, Helms, Jill A., Andrew A Smith, Anthony E Oro, Andrew A. Smith (474288), Oro Anthony E., Chang, Howard Y., Jemima L Whyte, Liu Bo, Howard Y Chang, Dhamdhere, Girija R, Evans Nick D., Evans, Nick D., Wilfred R. Manzano (474289), Oro, Anthony E., Nick D. Evans¤a, Smith Andrew A., Whyte Jemima L., Liu, Bo, Mark Y. Fang (474292), Wilfred R Manzano, Jill A. Helms (25398), Fang, Mark Y., Smith, Andrew A., Andrew A. Smith, Evans, Nick D, Helms, Jill A, Girija R. Dhamdhere (474291), Girija R. Dhamdhere, Jill A Helms, Mark Y. Fang¤b, Anthony E. Oro (474293), Jill A. Helms, Dhamdhere, Girija R., Mark Y Fang, Chang, Howard Y, Chang Howard Y., Jemima L. Whyte, Oro, Anthony E, Howard Y. Chang, Bo Liu (127343), Dhamdhere Girija R.   +57 more
core   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Endocrine Regulation in the Ovary by MicroRNA during the Estrous Cycle

Frontiers in Endocrinology, 2018
Hormonal control of the estrous cycle that occurs in therian mammals is essential for the production of a functional egg. Supporting somatic cell types found within the ovary, such as granulosa and theca cells, respond to endocrine signals to support ...
Derek Toms, Bo Pan, Julang Li, Julang Li
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

, 2020
Compartmentalization of diverse types of signaling molecules contributes to the precise coordination of signal propagation. The primary cilium fulfills this function by acting as a spatiotemporally confined sensory signaling platform.
Pia Aanstad, Omar Torres-Quesada, Philipp Tschaikner, Eduard Stefan, Florian Enzler   +4 more
core   +1 more source