Results 81 to 90 of about 568,795 (313)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

«ECOLOGICAL BOOMERANG» EFFECT IN HOSPITAL ENVIRONMENT

open access: yesAdvanced Engineering Research, 2012
Some dangerous, in terms of the man-made ecosystem operation, events in the hospital environment are presented. The microbiological factor, its transformation in the course of the diagnostic and treatment process, and human health implications are ...
Besarion C. Meskhi   +2 more
doaj  

Clinical and microbiological profile of pneumonia among children with congenital heart diseases at alexandria university children’s hospital

open access: yesBMC Infectious Diseases
Background Pneumonia is a significant cause of morbidity and mortality among children with congenital heart diseases (CHD). Consequently, the current study aimed to identify the prevalent pathogens causing pneumonia among children with CHD, as well as ...
Hani Mahmoud Adel   +4 more
doaj   +1 more source

Pediatric Non-COVID-19 Community-Acquired Pneumonia in COVID-19 Pandemic

open access: yesInternational Journal of General Medicine, 2021
Chienhsiu Huang Department of Internal Medicine, Division of Chest Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin Town, Chiayi County, TaiwanCorrespondence: Chienhsiu HuangDepartment of Internal Medicine, Division of Chest ...
Huang C
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Pediatric Neuromuscular Diseases Prevalence in Siriraj Hospital, Thailand's Largest Tertiary Referral Hospital

open access: yes, 2020
Objective: There are no epidemiological data on childhood neuromuscular diseases in Thailand. We aimed to estimate the proportion of NMDs among pediatric neurology patients in Siriraj Hospital and determine the specific diagnosis.
Apirada Thongsing   +3 more
core   +1 more source

A Large Multicenter Prospective Study of Community-Onset Healthcare Associated Bacteremic Urinary Tract Infections in the Era of Multidrug Resistance: Even Worse than Hospital Acquired Infections?

open access: yes, 2021
Publisher Copyright: © 2021, The Author(s).Introduction: Healthcare-associated (HCA) infections represent a growing public health problem. The aim of this study was to compare community-onset healthcare associated (CO-HCA) bacteremic urinary tract ...
for the REIPI/GEIRAS-GEMARA SEIMC ITUBRAS-2 Group
core   +1 more source

«ECOLOGICAL BOOMERANG» EFFECT IN HOSPITAL ENVIRONMENT

open access: yesВестник Донского государственного технического университета, 2018
Some dangerous, in terms of the man-made ecosystem operation, events in the hospital environment are presented. The microbiological factor, its transformation in the course of the diagnostic and treatment process, and human health implications are ...
Besarion C. Meskhi   +2 more
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Measuring the effect of enhanced cleaning in a UK hospital : a prospective cross-over study [PDF]

open access: yes, 2009
Increasing hospital-acquired infections have generated much attention over the last decade. There is evidence that hygienic cleaning has a role in the control of hospital-acquired infections.
Dancer, Stephanie J.   +14 more
core   +1 more source

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