Results 181 to 190 of about 2,543,243 (267)

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang, Fengfeng Xiao, Ruie Chen, Cuixia Lu, Yi Ju, Mingqing Yuan, Yunlu Dai, Liewei Wen   +7 more
wiley   +1 more source

Dendrimer-Derived Mimics of Host Defense Peptides Selectively Disrupt Cancer Cell Membranes for Melanoma Therapy. [PDF]

Pharmaceutics
Qian Y, Yang D, Lin X, Shen C, Zhang J, Xu J, Zhao Y, Zhu L, Kong H, Zhang M, Zhu Y, Zhou C, He J.   +12 more
europepmc   +1 more source

Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in Streptococcus mitis-oralis. [PDF]

Antibiotics (Basel), 2021
Yeaman MR, Chan LC, Mishra NN, Bayer AS.
europepmc   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Rumicidins are a family of mammalian host-defense peptides plugging the 70S ribosome exit tunnel. [PDF]

Nat Commun
Panteleev PV, Pichkur EB, Kruglikov RN, Paleskava A, Shulenina OV, Bolosov IA, Bogdanov IV, Safronova VN, Balandin SV, Marina VI, Kombarova TI, Korobova OV, Shamova OV, Myasnikov AG, Borzilov AI, Osterman IA, Sergiev PV, Bogdanov AA, Dontsova OA, Konevega AL, Ovchinnikova TV.   +20 more
europepmc   +1 more source

Strategies in Translating the Therapeutic Potentials of Host Defense Peptides. [PDF]

Front Immunol, 2020
Ting DSJ, Beuerman RW, Dua HS, Lakshminarayanan R, Mohammed I.   +4 more
europepmc   +1 more source

Tannic acid–metal biomaterials for skin repair: Principles, immune microenvironment modulation, and translational perspectives

BMEMat, EarlyView.
Tannic acid–metal materials are emerging as versatile wound biomaterials, but their value depends on more than multifunctionality. This review maps how tannic acid alone, free metal ions, and coordinated TA–metal systems differ in design logic, immune‐microenvironment effects, and translational potential, offering a practical framework for choosing ...
Shahid Mahmood, Nan Li, Dandan Yang, Chunhui Sun, Yu Wang, Dongzhou Wang, Congcong Zhang   +6 more
wiley   +1 more source

Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides-Current Developments in Structure-Activity Relationship. [PDF]

Int J Mol Sci
Andrés CMC, Pérez de la Lastra JM, Bustamante Munguira E, Andrés Juan C, Pérez-Lebeña E.   +4 more
europepmc   +1 more source

Applications of Biomaterials in Separators for Secondary Batteries

Carbon Energy, EarlyView.
In this review, biomaterial‐based separators are reviewed as sustainable alternatives to conventional polyolefin‐based separators. For 12 different natural polymers, spanning from Protista, Plantae, and Animalia, viable strategies for synthesizing biomass‐based separators are described.
Jongyoung Choi, Sung Cik Mun, Yong‐Seok Choi, Jong Ho Won   +3 more
wiley   +1 more source