Results 191 to 200 of about 2,543,243 (267)

Host defense peptides mitigate the spread of antibiotic resistance in physiologically relevant condition. [PDF]

Antimicrob Agents Chemother
Zhang M, Yang B, Shi J, Wang Z, Liu Y.
europepmc   +1 more source

Bile Salts Differentially Enhance Resistance of Enterohemorrhagic Escherichia coli O157:H7 to Host Defense Peptides. [PDF]

Infect Immun, 2021
Gadishaw-Lue C, Banaag A, Birstonas S, Francis AS, Barnett Foster D.   +4 more
europepmc   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Correction: Nazeer et al. Bacterial-Specific Aggregation and Killing of Immunomodulatory Host Defense Peptides. Pharmaceuticals 2021, 14, 839. [PDF]

Pharmaceuticals (Basel)
Nazeer N, Rodriguez-Lecompte JC, Ahmed M.   +2 more
europepmc   +1 more source

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

Chemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

Host defense peptides human β defensin 2 and LL-37 ameliorate murine necrotizing enterocolitis. [PDF]

iScience
Lueschow-Guijosa SR, Stanford AH, Berger JN, Gong H, Boly TJ, Jensen BAH, Nordkild P, Leegwater AJ, Wehkamp J, Underwood MA, McElroy SJ.   +10 more
europepmc   +1 more source

In Vitro and In Vivo Antibiotic Capacity of Two Host Defense Peptides. [PDF]

Antimicrob Agents Chemother, 2020
Arenas I, Ibarra MA, Santana FL, Villegas E, Hancock REW, Corzo G.   +5 more
europepmc   +1 more source

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network

Clinical Pharmacology &Therapeutics, EarlyView.
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang, Jashvant D Unadkat, Samuel LM Arnold, John K Fallon, Pouria Fattahi, Dan Dongeun Huh, Nicholas Ieronimakis, Edward J Kelly, Svetlana Lutsenko, Robert M Stroud, Jacqueline B Tiley, Jia Yang, Xujia Zhou, Hao Zhu, Rajini Rao, Kathleen M Giacomini, Lauren M Aleksunes   +16 more
wiley   +1 more source

Cloning and Functional Analysis of Skin Host Defense Peptides from Yakushima Tago's Brown Frog (Rana tagoi yakushimensis) and Development of Serum Endotoxin Detection System. [PDF]

Antibiotics (Basel)
Aono T, Tamura S, Suzuki Y, Imanara T, Niwa R, Yamane Y, Kobayashi T, Kikuyama S, Hasunuma I, Iwamuro S.   +9 more
europepmc   +1 more source