Results 161 to 170 of about 342,764 (287)

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

‘Host-directed therapy’ could treat infectious diseases – including COVID – and limit drug-resistance

, 2022
Christian Doerig, Jack Adderley, Genia Burchall, Tayla Williamson   +3 more
openalex   +1 more source

Deep variational graph autoencoders for novel host-directed therapy options against COVID-19. [PDF]

Artif Intell Med, 2022
Ray S, Lall S, Mukhopadhyay A, Bandyopadhyay S, Schönhuth A.   +4 more
europepmc   +1 more source

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

, 2021
Seónadh M. O’Leary, Ahmad Z. Bahlool, Gemma O’Connor, Sally‐Ann Cryan, Joseph Keane, Mary P. O’Sullivan   +5 more
openalex   +2 more sources

RENAL HETEROTRANSPLANTATION FROM BABOON TO MAN: EXPERIENCE WITH 6 CASES. [PDF]

, 1964
HITCHCOCK, CR, KIRKPATRICK, CH, MARCHIORO, TL, OGDEN, DA, PETERS, GN, PORTER, KA, RIFKIND, D, STARZL, TE, WADDELL, WR, WILSON, WE   +9 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Airborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral, QianFeng Xu, Natalie Eidenschink, Pareesha Haresh, Alessandra Nara de Souza Rastelli, Jeremy Goverman, Alexander Greer, Alan M. Lyons, Tayyaba Hasan   +8 more
wiley   +1 more source

Doxycycline host-directed therapy in human pulmonary tuberculosis. [PDF]

J Clin Invest, 2021
Miow QH, Vallejo AF, Wang Y, Hong JM, Bai C, Teo FS, Wang AD, Loh HR, Tan TZ, Ding Y, She HW, Gan SH, Paton NI, Lum J, Tay A, Chee CB, Tambyah PA, Polak ME, Wang YT, Singhal A, Elkington PT, Friedland JS, Ong CW.   +22 more
europepmc   +1 more source

Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers [PDF]

, 2016
Robert S. Wallis, Markus Maeurer, Peter Mwaba, Jeremiah Chakaya, Roxana Rustomjee, Giovanni Battista Migliori, Ben J. Marais, Marco Schito, Gavin Churchyard, Soumya Swaminathan, Michael Höelscher, Alimuddin Zumla   +11 more
openalex   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source