Results 181 to 190 of about 342,764 (287)

Host-Directed Therapy and Drug Repurposing in Tuberculosis: A Scoping Review of Emerging Adjunctive Strategies

Prajjwol Luitel, Ishwor Thapaliya
openalex   +2 more sources

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

Advanced Materials, EarlyView.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang, Xinzhi Liang, Tiandi Xiong, Zheng Zhong, Ning Zhang, Boguang Yang, Dong Li, Qiongjiao Zeng, Xian Chen, Yiting Lei, Shangsi Chen, Chao Zheng, Liu Yang, Wei Huang, Rocky S. Tuan, Denghui Xie, Zhong Alan Li   +16 more
wiley   +1 more source

B-cell-directed therapy for chronic graft-versus-host disease

Haematologica, 2010
Caron A. Jacobson, Jerome Ritz
doaj   +1 more source

Don't Stress: We're One Step Closer to Host-Directed Therapy for Influenza. [PDF]

Am J Respir Cell Mol Biol
Hook JL.
europepmc   +1 more source

Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease. [PDF]

Elife, 2022
Costa VV, Sugimoto MA, Hubner J, Bonilha CS, Queiroz-Junior CM, Gonçalves-Pereira MH, Chen J, Gobbetti T, Libanio Rodrigues GO, Bambirra JL, Passos IB, Machado Lopes CE, Moreira TP, Bonjour K, Melo RCN, Oliveira MAP, Andrade MVM, Sousa LP, Souza DG, Santiago HDC, Perretti M, Teixeira MM.   +21 more
europepmc   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Mesenchymal Stromal Cells: an Antimicrobial and Host-Directed Therapy for Complex Infectious Diseases. [PDF]

Clin Microbiol Rev, 2021
Shaw TD, Krasnodembskaya AD, Schroeder GN, Zumla A, Maeurer M, O'Kane CM.   +5 more
europepmc   +1 more source

Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites [PDF]

, 2018
Sanjay Varikuti, Bijay Kumar Jha, Greta Volpedo, Nathan Ryan, Gregory Halsey, Omar Hamza, Bradford S. McGwire, Abhay R. Satoskar   +7 more
openalex   +1 more source

The organ transplanted patient - immunological concepts and immunosuppression [PDF]

, 1991
Husberg, BS, Klintmalm, GBG, Starzl, TE
core  

Recent Advances in Electrospun Nanofibers for Triboelectric Nanogenerators: Performance Enhancement Strategies and Emerging Applications

Advanced Materials, EarlyView.
This review highlights recent advances in electrospun nanofiber‐based triboelectric nanogenerators, emphasizing how material design, fiber architecture, and interface engineering collectively enhance output performance and mechanical durability. Key developments in porous, aligned, core‐shell, and hierarchical nanofibers are discussed alongside ...
MD Fajla Rabbi, Jee Hwan Ahn, Duy Linh Vu, Kyoung Kwan Ahn   +3 more
wiley   +1 more source