Results 131 to 140 of about 803,197 (352)

MEDNER.DE: Medicinal Product Entity Recognition in German-Specific Contexts

IEEE Access
Named entity recognition (NER) is an area of significant interest in the field of medicine, particularly for identifying specific terms such as medicinal products, medical events and diagnoses from doctors’ letters. However, training NER models in
Farnaz Zeidi, Manuela Messelhauber, Roman Christof, Xing David Wang, Ulf Leser, Dirk Mentzer, Renate Konig, Liam Childs   +7 more
doaj   +1 more source

Trends in mathematical modeling of host–pathogen interactions

Cellular and Molecular Life Sciences, 2019
Pathogenic microorganisms entail enormous problems for humans, livestock, and crop plants. A better understanding of the different infection strategies of the pathogens enables us to derive optimal treatments to mitigate infectious diseases or develop ...
Jan Ewald, Patricia Sieber, R. Garde, Stefan N. Lang, S. Schuster, B. Ibrahim   +5 more
semanticscholar   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Natural history of Arabidopsis thaliana and oomycete symbioses [PDF]

, 2008
Molecular ecology of plant–microbe interactions has immediate significance for filling a gap in knowledge between the laboratory discipline of molecular biology and the largely theoretical discipline of evolutionary ecology.
A. Falk, A. H. Ellingboe, A. H. Ellingboe, A. J. Slusarenko, A. P. Rehmany, A. P. Rehmany, A. Riethmüller, A. Roetschi, Arabidopsis Genome Initiative, B. F. Holt, B. M. Tyler, C. Azevedo, C. D. Preston, C. Damgaard, D. Jirage, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. G. Bakker, E. Gäumann, E. Koch, E. O. Wilson, E. Speulman, Eric B. Holub, G. Lindau, H. Jönsson, H. Takahashi, H. Voglmayr, H.-M. Chou, J. E. Parker, J. E. Parker, J. Glazebrook, J. Glazebrook, J. M. McDowell, J. M. McDowell, J. N. Thompson, J. N. Thompson, J. N. Thompson, J. O. Borevitz, J. Silvertown, J. Song, J. Staal, J. Win, K. A. Shen, K. Century, K. Kazan, K. Lawton, K. S. Century, K. S. Thompson, L. E. Rose, M. A. Botella, M. A. Botella, M. B. Cooley, M. Damme Van, M. G. M. Aarts, M. Göker, M. H. Borhan, M. H. Borhan, M. J. Austin, M. Tör, N. Aarts, N. Gunn, O. Constantinescu, P. Ayers, P. D. Bittner-Eddy, P. Prusinkiewicz, P. R. Muskett, P. Tornero, Q. H. Shen, R. F. Warren, R. F. Warren, R. Gomulkiewicz, R. L. Allen, R. M. Clark, S. Kamoun, S. McCouch, S. R. Grant, S. Segal, T. Eulgem, T. Eulgem, T. Mitchell-Olds, W. Gassmann, X. Tang   +87 more
core   +2 more sources

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Impact of the elderly lung mucosa on Mycobacterium tuberculosis transcriptional adaptation during infection of alveolar epithelial cells

Microbiology Spectrum
Tuberculosis is one of the leading causes of death due to a single infectious agent. Upon infection, Mycobacterium tuberculosis (M.tb) is deposited in the alveoli and encounters the lung mucosa or alveolar lining fluid (ALF).
Angélica M. Olmo-Fontánez, Anna Allué-Guardia, Andreu Garcia-Vilanova, Jeremy Glenn, Shu-Hua Wang, Robert E. Merritt, Larry S. Schlesinger, Joanne Turner, Yufeng Wang, Jordi B. Torrelles   +9 more
doaj   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Identification of amino acid residues in polymerase PB2 responsible for differential replication and pathogenicity of avian influenza virus H5N1 isolated from human and cattle in Texas, US

Emerging Microbes and Infections
Highly pathogenic avian influenza viruses (HPAIV) pose serious public health concerns. In March 2024, a first-time outbreak of HPAIV H5N1 in dairy cattle herds was reported in the United States (US).
Mahmoud Bayoumi, Ramya S. Barre, Ruby A. Escobedo, Vinay Shivanna, Nathanial Jackson, Chengjin Ye, Adolfo García-Sastre, Ahmed Mostafa, Luis Martinez-Sobrido   +8 more
doaj   +1 more source

Centennial Review: Recent developments in host-pathogen interactions during necrotic enteritis in poultry

, 2021
Nima K. Emami, Rami A. Dalloul
openalex   +1 more source

Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions

eLife, 2018
Uropathogenic E. coli (UPEC), which cause urinary tract infections (UTI), utilize type 1 pili, a chaperone usher pathway (CUP) pilus, to cause UTI and colonize the gut.
Caitlin N. Spaulding, H. Schreiber, Weili Zheng, K. Dodson, Jennie E. Hazen, Matt S. Conover, Fengbin Wang, P. Svenmarker, Areli Luna-Rico, O. Francetic, Magnus Andersson, S. Hultgren, E. Egelman   +12 more
semanticscholar   +1 more source