Results 11 to 20 of about 364,753 (312)

Senescence and Host–Pathogen Interactions [PDF]

Cells, 2020
Damage to our genomes triggers cellular senescence characterised by stable cell cycle arrest and a pro-inflammatory secretome that prevents the unrestricted growth of cells with pathological potential. In this way, senescence can be considered a powerful innate defence against cancer and viral infection.
Daniel Humphreys, Mohamed ElGhazaly, Teresa Frisan   +2 more
openaire   +6 more sources

Phosphoinositides and host–pathogen interactions [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015
Phosphoinositides control key cellular processes including vesicular trafficking and actin polymerization. Intracellular bacterial pathogens manipulate phosphoinositide metabolism in order to promote their uptake by target cells and to direct in some cases the biogenesis of their replication compartments.
Pizarro-Cerdá, Javier, Kühbacher, Andreas, Cossart, Pascale   +2 more
openaire   +3 more sources

Host-Pathogen Interactions of Retroviruses [PDF]

Molecular Biology International, 2012
Retroviruses, such as HIV-1, are enveloped RNA viruses that use the enzyme reverse transcriptase (RT) to make a DNA copy of their RNA genome during replication in the host cell. The retrovirus life cycle is generally divided into two distinct phases: the early and late phase.
Waheed, Abdul A., Brass, Abraham L., Gummuluru, Suryaram, Tachedjian, Gilda   +3 more
openaire   +2 more sources

Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions [PDF]

, 2021
The alveolates (Superphylum Alveolata) comprise a group of primarily single-celled eukaryotes that have adopted extremely diverse modes of nutrition, such as predation, photoautotrophy and parasitism.
Lange, S., Erlingsdóttir, Ásthildur, Kristmundsson, Árni   +2 more
core   +1 more source

No better time to FRET: shedding light on host pathogen interactions [PDF]

, 2010
Understanding the spatio-temporal subversion of host cell signaling by bacterial virulence factors is key to combating infectious diseases. Following a recent study by Buntru and co-workers published in BMC Biology, we review how fluorescence (Forster ...
Leong, J.M., Goguen, J.D., Goguen, JD, Leong, JM, Hayward, RD, Hayward, Richard D.   +5 more
core   +1 more source

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages. [PDF]

, 2008
BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon, Castagnoli, PR, Mattia Pelizzola (20247), Castagnoli, Paola Ricciardi, Pelizzola Mattia, Foti, M, Maria Foti, Butcher, Philip, Neyrolles, Olivier, Neyrolles, O, Antoine Tanne, Simon J Waddell, Olivier Neyrolles, Pelizzola, M, Tailleux, L, Simon J. Waddell, Antoine Tanne (272975), Philip D Butcher (16047203), Maria Foti (20249), Neil G. Stoker, Stoker Neil G., Waddell, SJ, Tailleux Ludovic, Tailleux, Ludovic, Gicquel, Brigitte, Simon Waddell (4462816), Castagnoli Paola Ricciardi, Brigitte Gicquel, Philip D Butcher, Tanne Antoine, Alessandra Mortellaro (272973), Mortellaro, A, Gicquel Brigitte, Stoker, Neil, Philip D. Butcher, Butcher, PD, Tanne, Antoine, Olivier Neyrolles (72204), Tanne, A, Mortellaro, Alessandra, Paola Ricciardi Castagnoli (16048310), Ludovic Tailleux, Michael Withers (272974), Neyrolles Olivier, Withers Michael, Foti, Maria, Waddell Simon J., Stoker, NG, Michael Withers, Pelizzola, Mattia, Mortellaro Alessandra, Brigitte Gicquel (31454), Ludovic Tailleux (72195), Neil G Stoker (16048313), Alessandra Mortellaro, Neil G Stoker, Foti Maria, Gicquel, B, Butcher Philip D., Withers, M, Mattia Pelizzola, Paola Ricciardi Castagnoli, Withers, Michael   +62 more
core   +1 more source

Diet quality determines interspecific parasite interactions in host populations [PDF]

, 2014
The widespread occurrence of multiple infections and the often vast range of nutritional resources for their hosts allow that interspecific parasite interactions in natural host populations might be determined by host diet quality. Nevertheless, the role
Lange, B., Ebert, Dieter, Reuter, M., Reuter, Max, Decaestecker, Ellen, Decaestecker, E., Muylaert, Koenraad, Muylaert, K., Lange, Benjamin   +8 more
core   +1 more source

PHI-base: the pathogen-host interactions database. [PDF]

, 2019
The pathogen-host interactions database (PHI-base) is available at www.phi-base.org. PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions reported in peer reviewed ...
Wood, V., Yates, A. D., Hassani-Pak, K., Rutherford, K., Pedro, H., Seager, J., De Silva, N., Venkatesh, S. Y, Urban, M., Martinez, M. C., Cuzick, A., Hammond-Kosack, K. E.   +11 more
core   +2 more sources

Host specificity and genetics of host resistance in the "Daphnia-Pasteuria" host-parasite system [PDF]

, 2012
Antagonistic coevolution plays an important role in a large number of evolutionary and ecological phenomena. Furthermore, according to the Red Queen Theory coevolution between hosts and their parasites may explain the maintenance of sexual reproduction ...
Luijckx, Pepijn
core   +1 more source

Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions [PDF]

, 2011
Background Infection processes consist of a sequence of steps, each critical for the interaction between host and parasite. Studies of host-parasite interactions rarely take into account the fact that different steps might be influenced by different ...
Ebert, Dieter, Dieter Ebert, Ben-Ami, Frida, Laforsch Christian, Duneau David, Ebert Dieter, David Duneau, Laforsch, C., Luijckx Pepijn, Duneau, David, Luijckx, P., Ben-Ami, F., Luijckx, Pepijn, Frida Ben-Ami, Pepijn Luijckx, Duneau, D., Ben-Ami Frida, Christian Laforsch, Laforsch, Christian   +18 more
core   +1 more source