Results 241 to 250 of about 713,544 (377)

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Host-Pathogen Interaction in Rice-Bacterial Blight Pathosystem [PDF]

, 2008
Debabrata Nayak, Lotan Kumar Bose, Pothireddy Reddy, Parsuram Nayak   +3 more
openalex   +1 more source

Effects of Body Condition and Ectoparasitism on Host-Pathogen Interactions of Heteromyid Rodents. [PDF]

Pathogens
Beristain-Ruiz DM, Márquez-Chacón AK, Vital-García C, Figueroa-Millán JV, Lira-Amaya JJ, Aristizabal JF, Olivas-Sánchez MP, Gatica-Colima AB, Martínez-Calderas JM, Quezada-Casasola A, Alvarado-Robles B, Alonso-Mendoza VM.   +11 more
europepmc   +1 more source

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

Possible Effects of Microbial Ecto-Nucleoside Triphosphate Diphosphohydrolases on Host-Pathogen Interactions [PDF]

, 2008
Fiona M. Sansom, Simon C. Robson, Elizabeth L. Hartland   +2 more
openalex   +1 more source

Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock. [PDF]

Front Cell Infect Microbiol
Weldearegay YB, Brogaard L, Rautenschlein S, Meens J, Valentin-Weigand P, Schaaf D.   +5 more
europepmc   +1 more source

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

Advanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde, Oluwadamilola Fatimat Babatunde, Adeel Ahmed, Wilmara Salgado‐Pabon, David J Beebe, Sheena C. Kerr   +5 more
wiley   +1 more source

Applying 3D cultures and high-throughput technologies to study host-pathogen interactions. [PDF]

Front Immunol
De Martinis ECP, Alves VF, Pereira MG, Andrade LN, Abichabki N, Abramova A, Dannborg M, Bengtsson-Palme J.   +7 more
europepmc   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Molecular mechanisms of the human pathogen <i>Candida glabrata</i> involved in the interaction with the host [PDF]

, 2008
Pia Schmidt
openalex   +1 more source