Results 291 to 300 of about 803,197 (352)

Understanding Host-Pathogen Interactions in Congenital Chagas Disease Through Transcriptomic Approaches. [PDF]

Pathogens
Cáceres TM, Patiño LH, Ramírez JD.
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Effects of Body Condition and Ectoparasitism on Host-Pathogen Interactions of Heteromyid Rodents. [PDF]

Pathogens
Beristain-Ruiz DM, Márquez-Chacón AK, Vital-García C, Figueroa-Millán JV, Lira-Amaya JJ, Aristizabal JF, Olivas-Sánchez MP, Gatica-Colima AB, Martínez-Calderas JM, Quezada-Casasola A, Alvarado-Robles B, Alonso-Mendoza VM.   +11 more
europepmc   +1 more source

Interaction of pathogens with host cholesterol metabolism

, 2014
Dmitri Sviridov, Michael Bukrinsky
openalex   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Divergent host-pathogen interactions in neurolisteriosis: cytosolic replication vs. phagosomal dormancy of Listeria monocytogenes in CNS macrophages. [PDF]

Acta Neuropathol
Tavares-Gomes L, Polidori M, Monney C, Neuhaus G, Vidondo B, Witz G, Hemphill A, Oevermann A.   +7 more
europepmc   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Applying 3D cultures and high-throughput technologies to study host-pathogen interactions. [PDF]

Front Immunol
De Martinis ECP, Alves VF, Pereira MG, Andrade LN, Abichabki N, Abramova A, Dannborg M, Bengtsson-Palme J.   +7 more
europepmc   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Primary cell culture systems to investigate host-pathogen interactions in bacterial respiratory tract infections of livestock. [PDF]

Front Cell Infect Microbiol
Weldearegay YB, Brogaard L, Rautenschlein S, Meens J, Valentin-Weigand P, Schaaf D.   +5 more
europepmc   +1 more source