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Diverse reactivity of maleimides in polymer science and beyond
Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source
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Host defense peptides in burns
Burns, 2004Overuse of antibiotics and failure to apply basic infection control policies and procedures have contributed to the increasing multi-drug resistance of many nosocomial pathogens. The alarming increase of multi-drug-resistant bacteria (e.g. Pseudomonas aeruginosa, methicilin-resistant Staphylococci, vancomycin-resistant Enterococci) causes infected ...
L, Steinstraesser +3 more
openaire +2 more sources
Developmental & Comparative Immunology, 2013
Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense of many organisms.
Cuperus, Tryntsje +3 more
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Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense of many organisms.
Cuperus, Tryntsje +3 more
openaire +4 more sources
Antimicrobial Peptides: Amphibian Host Defense Peptides
Current Medicinal Chemistry, 2019Antimicrobial Peptides (AMPs) are one of the most common components of the innate immune system that protect multicellular organisms against microbial invasion. The vast majority of AMPs are isolated from the frog skin. Anuran (frogs and toads) skin contains abundant AMPs that can be developed therapeutically.
Jiri, Patocka +4 more
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Cationic host defense (antimicrobial) peptides
Current Opinion in Immunology, 2006Members of the cationic host defense (antimicrobial) peptide family are widely distributed in nature, existing in organisms from insects to plants to mammals and non-mammalian vertebrates. Although many demonstrate direct antimicrobial activity against bacteria, fungi, eukaryotic parasites and/or viruses, it has been established that cationic peptides ...
Kelly L, Brown, Robert E W, Hancock
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Antiviral Activities of Human Host Defense Peptides
Current Medicinal Chemistry, 2020Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout nature. As they participate in a number of different aspects of innate immunity in mammals, they have been termed Host Defense Peptides (HDPs).
Gill Diamond, David C Brice
exaly +3 more sources
Modulation of Host Defense Peptide-Mediated Human Mast Cell Activation by LPS [PDF]
Innate Immunity, 2016 Human β-defensin3 (hBD3) and the cathelicidin LL-37 are host defense peptides (HDPs) that directly kill microbes and display immunomodulatory/wound-healing properties via the activation of chemokine, formylpeptide and epidermal growth factor receptors on
Hydar Ali +2 more
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Host Defense Peptides in the Oral Cavity
2008Publisher Summary Host defense peptides (HDPs) are important in defense of tissues throughout the human mouth. Like resident microbial populations, HDPs are diverse, species-specific, and site-specific, and they have evolved in response to selection pressures exerted by resident and pathogenic microbial populations.
Devine, Deirdre, Cosseau, Celine
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Host defense peptides: front-line immunomodulators
Trends in Immunology, 2014Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now widely recognized for their multifunctional roles in both the innate and adaptive immune responses. Their diverse immunomodulatory capabilities include the modulation of pro- and anti-inflammatory responses, chemoattraction, enhancement of extracellular and ...
Sarah C, Mansour +2 more
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2009
In this chapter, the authors explains genetic, structural and functional relatives of non-fish host defense peptides in fish, and they devote a portion of this discussion to each of these topics. A great leap in understanding host defense peptides in fish came when genetic techniques replaced the previously-utilised tedious and expensive purification ...
Patrzykat, A., Hancock, R. E. W.
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In this chapter, the authors explains genetic, structural and functional relatives of non-fish host defense peptides in fish, and they devote a portion of this discussion to each of these topics. A great leap in understanding host defense peptides in fish came when genetic techniques replaced the previously-utilised tedious and expensive purification ...
Patrzykat, A., Hancock, R. E. W.
openaire +2 more sources